Patent Application
App. No. 12/425,874
ANTIBODIES AGAINST ERBB3 AND USES THEREOF
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Abstract
The present invention provides a novel class of monoclonal antibodies which bind ErbB3 receptor and inhibits various ErbB3 functions. For example, the antibodies described herein are capable of binding to ErbB3 and inhibiting EGF-like ligand mediated phosphorylation of the receptor.
Claims (2)
1 . An isolated monoclonal antibody or antigen binding portion thereof that binds to ErbB3 and inhibits EGF-like ligand mediated phosphorylation of ErbB3.
2 - 58 . (canceled)
Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 24, 2010
From: DYAX CORP.
To: MERRIMACK PHARMACEUTICALS, INC.
Reel/Frame 023980/0797 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Nov 13, 2009
From: SCHOEBERL, BIRGIT; NIELSEN, ULRIK; FELDHAUS, MICHAEL
To: MERRIMACK PHARMACEUTICALS, INC.
Reel/Frame 023517/0811 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Nov 13, 2009
From: MURUGANANDAM, ARUMUGAM; BUCKLER, DAVID
To: DYAX CORP.
Reel/Frame 023517/0839 →