IP Library Granted Patent US 8,647,857
Granted Patent B2
US 8,647,857 · App. 12/433,701 · Granted Feb 11, 2014

Processes for the digestion of colanic acid

Inventor: Nancy Smyth Templeton (Carrollton, TX)
Assignee: Gradalis, Inc.
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Quick Facts
Patent No.
US 8,647,857
App. No.
12/433,701
Granted
Feb 11, 2014
Kind
B2
Abstract

The present disclosure generally relates to processes employing polypeptides having colanic acid-degrading activity. The processes generally involve contacting a biological material with a polypeptide capable of digesting colanic acid. Additional process steps, such as chromatographic separation steps, are also described.

Claims (4)

1. A process for digesting colanic acid in a biological material, the process comprising contacting the biological material under conditions that cause colonic acid digestion with a polypeptide having at least 95% sequence identity to SEQ ID NO: 2 that digests colanic acid.

2. The process of claim 1 , wherein the polypeptide is a recombinant polypeptide.

3. The process of claim 1 , wherein the polypeptide comprises an amino acid sequence having at least 98% sequence identity to SEQ ID NO: 2, and conservative amino acid substitutions thereof.

4. The process of claim 1 , wherein the polypeptide is SEQ ID NO: 2.

Assignments (4)
PATENT SECURITY AGREEMENT Recorded Dec 20, 2019
From: GRADALIS, INC.
To: HC INNOVATIVE PARTNERS, LP, AS COLLATERAL AGENT
Reel/Frame 051396/0366 →
MERGER Recorded May 3, 2018
From: STRIKE BIO, INC.
To: GRADALIS, INC.
Reel/Frame 045709/0406 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 6, 2015
From: GRADALIS, INC.
To: STRIKE BIO, INC.
Reel/Frame 035603/0731 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 1, 2009
From: TEMPLETON, NANCY SMYTH
To: GRADALIS,INC.
Reel/Frame 022760/0578 →
Continuity (3)
Provisional Application 61125916 · Apr 30, 2008
Provisional Application 61125923 · Apr 30, 2008
Related Publication 20100075404A1 · Mar 25, 2010