IP Library Granted Patent US 8,133,198
Granted Patent B2
US 8,133,198 · App. 12/439,212 · Granted Mar 13, 2012

Medical fluid injector having a thermo-mechanical drive

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Quick Facts
Patent No.
US 8,133,198
App. No.
12/439,212
Granted
Mar 13, 2012
Kind
B2
Abstract

A medical fluid injector and methods for operation thereof. In certain embodiments, the medical fluid injector includes a medium that is expandable and contractible in response to a thermal gradient, a thermal device coupled to the medium, and a syringe interface coupled to the medium. The thermal device may include a heater, a cooler, or a combination thereof.

Claims (40)

1. A medical fluid injector, the injector comprising:

a medium that is expandable and contractible in response to a thermal gradient;

a thermal device in thermal communication with the medium, wherein the thermal device comprises a heater and a cooler;

a controller in communication with each of the heater and the cooler; and

a syringe interface coupled to the medium, wherein the syringe interface is movable by the medium, wherein the controller signals the heater to move the syringe interface in a first direction, and wherein the controller signals the cooler to move the syringe interface in a second direction.

2. The injector of claim 1 , wherein the medium is a solid.

3. The injector of claim 1 , wherein the medium is a fluid.

4. The injector of claim 3 , wherein the fluid comprises a substantially incompressible liquid that is disposed within a generally closed system, and wherein the syringe interface is coupled to a fluidly movable member within the generally closed system.

5. The injector of claim 4 , wherein the substantially incompressible liquid comprises alcohol.

6. The injector of claim 1 , further comprising:

a fluid thermo-mechanical actuator that comprises a pressure vessel, a conduit coupled to the pressure vessel, a barrel coupled to the conduit, and a piston disposed movably in the barrel, and wherein the syringe interface is coupled to the piston, and wherein each of the heater and cooler is in thermal communication with the pressure vessel.

7. The injector of claim 1 , wherein the medium comprises first and second mediums isolated from one another, and wherein the thermal device is disposed between the first and second mediums.

8. The injector of claim 7 , wherein the first and second mediums comprise first and second fluids disposed in first and second chambers, and wherein the first and second chambers are fluidly coupled to opposite sides of a piston coupled to the syringe interface.

9. The injector of claim 1 , wherein the thermal device comprises a thermoelectric device.

10. The injector of claim 1 , further comprising:

a syringe in contact with the syringe interface.

11. The injector of claim 1 , further comprising:

a sensor.

12. The injector of claim 11 , wherein the controller interacts with the sensor.

13. The injector of claim 12 , wherein the controller receives at least one feedback signal from the sensor indicative of at least one of a temperature of the medium, a pressure of the medium, a position of the syringe interface, a velocity of the syringe interface, and a flow rate associated with a movement of the syringe interface.

14. The injector of claim 10 , wherein the syringe comprises a barrel and a plunger disposed within and movable relative to the barrel, wherein the controller signals the thermal device to move the syringe interface in the first direction which in turn moves the plunger in one direction, and wherein the controller signals the thermal device to move the syringe interface in the second direction which in turn moves the plunger in another direction.

15. The injector of claim 14 , wherein the first direction is associated with a discharge of medical fluid from the syringe, and wherein the second direction is associated with a loading of medical fluid into the syringe.

16. The injector of claim 14 , wherein the syringe interface is coupled with a push rod of the syringe, and wherein the push rod extends from the plunger of the syringe and interfaces with the syringe interface.

17. The injector of claim 1 , wherein the medium comprises first and second fluids within first and second reservoirs, respectively, wherein the thermal device is in thermal communication with each of the first and second reservoirs, wherein the injector further comprises an actuator, wherein the actuator comprises a piston, a barrel, and the syringe interface, wherein a movable seal exists between the piston and the barrel, wherein the piston is coupled to the syringe interface, wherein the first reservoir is fluidly connected with a first side of the piston, wherein the second reservoir is fluidly connected to a second side of the piston, and wherein the first and second sides of the piston are fluidly isolated from each other by the seal between the piston and the barrel.

18. The injector of claim 17 , wherein a first operation of the thermal device transfers heat between the first and second reservoirs such that the first medium pushes on the piston head and the second medium pulls on the piston head to move the piston head in the first direction, and wherein a second operation of the thermal device transfers heat between the first and second reservoirs such that the first medium pulls on the piston head and the second medium pushes on the piston head to move the piston head in the second direction that is opposite of the first direction.

19. A method of operation for a medical fluid injector, the method comprising:

interacting a first fluid with a first side of a piston; and

moving the piston in each of first and second axial directions solely by fluid pressure acting directly on the piston, wherein the moving comprises:

expanding the first fluid to move the piston in the first axial direction, wherein the expanding of the first fluid comprises heating the first fluid;

advancing a plunger of a syringe in one direction in response to movement of the piston resulting from the expanding of the first fluid;

contracting the first fluid to move the piston in the second axial direction, wherein the contracting of the first fluid comprises cooling the first fluid; and

advancing the plunger of the syringe in another direction in response to movement of the piston resulting from the contracting of the first fluid.

20. The method of claim 19 , wherein fluid pressure provided by each of the expanding and contracting of the first fluid acts on the first side of the piston.

21. The method of claim 20 , wherein the moving further comprises directing air from a pressure vessel against a second side of the piston during each of the expanding and contracting of the first fluid.

22. The method of claim 20 , further comprising:

interacting a second fluid with a second side of the piston that is opposite of the first side, wherein the moving further comprises:

contracting the second fluid during the expanding of the first fluid, wherein the contracting of the second fluid comprises cooling the second fluid; and

expanding the second fluid during the contracting of the first fluid, wherein the expanding of the second fluid comprises heating the second fluid.

23. The method of claim 19 , wherein the advancing of the plunger of the syringe in the one direction comprises expelling a contrast agent from the syringe.

24. The method of claim 19 , wherein the advancing of the plunger of the syringe in the one direction comprises expelling a radiopharmaceutical from the syringe.

Assignments (2)
RELEASE OF PATENT SECURITY INTERESTS RECORDED AT REEL 032480, FRAME 0001 Recorded Nov 16, 2023
From: DEUTSCHE BANK AG NEW YORK BRANCH, AS COLLATERAL AGENT
To: THERAKOS, INC.; MALLINCKRODT INTERNATIONAL FINANCE S.A.; MALLINCKRODT CB LLC; MALLINCKRODT FINANCE GMBH; MALLINCKRODT US HOLDINGS LLC (F/K/A MALLINCKRODT US HOLDINGS INC.); MALLINCKRODT CARRIBEAN, INC.; MALLINCKRODT US POOL LLC; MNK 2011 LLC (F/K/A MALLINCKRODT INC.); LUDLOW LLC (F/K/A LUDLOW CORPORATION); CNS THERAPEUTICS, INC.; MALLINCKRODT ENTERPRISES HOLDINGS LLC (F/K/A MALLINCKRODT ENTERPRISES HOLDINGS, INC.); MALLINCKRODT ENTERPRISES LLC; MALLINCKRODT LLC; LAFAYETTE PHARMACEUTICALS LLC; LIEBEL-FLARSHEIM COMPANY LLC; MALLINCKRODT BRAND PHARMACEUTICALS LLC (F/K/A MALLINCKRODT BRAND PHARMACEUTICALS, INC.); MALLINCKRODT VETERINARY, INC.; MALLINCKRODT US HOLDINGS LLC; IMC EXPLORATION COMPANY; MEH, INC.; MALLINCKRODT HOSPITAL PRODUCTS IP UNLIMITED COMPANY (F/K/A MALLINCKRODT HOSPITAL PRODUCTS IP LIMITED); MALLINCKRODT ARD IP UNLIMITED COMPANY (F/K/A MALLINCKRODT ARD IP LIMITED); OCERA THERAPEUTICS LLC (F/K/A OCERA THERAPEUTICS, INC.); SPECGX LLC; STRATATECH CORPORATION; SUCAMPO PHARMA AMERICAS LLC; VTESSE LLC (F/K/A VTESSE INC.); MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED; MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY (F/K/A MALLINCKRODT PHARMA IP TRADING D.A.C.); INFACARE PHARMACEUTICAL CORPORATION; ST SHARED SERVICES LLC; IKARIA THERAPEUTICS LLC; INO THERAPEUTICS LLC
Reel/Frame 065609/0322 →
RELEASE OF SECURITY INTEREST Recorded Nov 30, 2015
From: DEUTSCHE BANK AG NEW YORK BRANCH, AS COLLATERAL AGENT
To: LIEBEL-FLARSHEIM COMPANY LLC
Reel/Frame 037172/0094 →