IP Library Granted Patent US 8,431,909
Granted Patent B2
US 8,431,909 · App. 12/441,919 · Granted Apr 30, 2013

Self-aligning radioisotope elution system

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Quick Facts
Patent No.
US 8,431,909
App. No.
12/441,919
Granted
Apr 30, 2013
Kind
B2
Abstract

A radioisotope elution system including a radioisotope generator having an alignment structure. The alignment structure may be configured to interface with a complementary alignment structure of an auxiliary radiation shield assembly.

Claims (16)

1. A radioisotope generator comprising:

a generator body that includes an elution column, and at least one radiation shielding material selected from depleted uranium, tungsten, tungsten impregnated plastic, or lead;

a needle assembly comprising an input needle and an output needle, wherein the input needle is fluidly interconnected with an input to the elution column, and the output needle is fluidly interconnected with an output from the elution column; and

a cap having a recess defined therein, wherein the recess is in the form of a cylinder having both a base and walls that are generally perpendicular to the base, and wherein both the input needle and the output needle of the needle assembly are located within the same recess defined in the cap.

2. The radioisotope generator of claim 1 , wherein the walls of the recess are substantially parallel to the needle.

3. The radioisotope generator of claim 1 in combination with a radiation shield, wherein the radiation shield includes a lid having opposing top and bottom surfaces, the lid including a male alignment structure extending downward from the bottom surface, the structure defining a cylinder that is complementary to the recess of the radioisotope generator cap such that the structure is configured to mate with the recess, wherein the lid comprises at least one radiation shielding material selected from depleted uranium, tungsten, tungsten impregnated plastic, or lead.

4. The radioisotope generator and radiation shield of claim 3 , wherein the lid includes a first aperture that extends through the lid in a direction that is substantially parallel to an input needle on the radioisotope generator when the lid is mated with the radioisotope generator cap.

5. The radioisotope generator and radiation shield of claim 4 , wherein the lid includes a second aperture that extends through the lid in a direction that is substantially parallel to an output needle on the radioisotope generator when the lid is mated with the radioisotope generator cap.

6. The radioisotope generator and radiation shield of claim 3 , wherein the radiation shield comprises an auxiliary shield having a receptacle defined therein for receiving the radioisotope generator, and wherein the lid is shaped such that the lid can translate into the receptacle and mate with the radioisotope generator cap.

7. The radioisotope generator and radiation shield of claim 3 , wherein the radioisotope generator is configured to support at least part of a weight of the lid when the lid is mated with the radioisotope generator cap.

8. The radioisotope generator and radiation shield of claim 3 , wherein at least a portion of the radiation shield is over-molded in a polymer.

9. The radioisotope generator of claim 1 , wherein the base of the recess is oval.

10. The radioisotope generator of claim 9 , wherein the recess has a single plane of symmetry that is generally perpendicular to the base.

11. The radioisotope generator of claim 1 , wherein the cap includes a plurality of tabs that facilitate coupling the cap to the generator body.

12. The radioisotope generator of claim 1 , further comprising a lifting strap coupled to the generator body at a first strap support and a second strap support.

13. The radioisotope generator of claim 12 , wherein the cap includes a first support channel that engages the first strap support and a second support channel that engages the second strap support to align the cap with respect to the generator body.

Assignments (7)
RELEASE OF PATENT SECURITY INTERESTS RECORDED AT REEL 032480, FRAME 0001 Recorded Nov 16, 2023
From: DEUTSCHE BANK AG NEW YORK BRANCH, AS COLLATERAL AGENT
To: THERAKOS, INC.; MALLINCKRODT INTERNATIONAL FINANCE S.A.; MALLINCKRODT CB LLC; MALLINCKRODT FINANCE GMBH; MALLINCKRODT US HOLDINGS LLC (F/K/A MALLINCKRODT US HOLDINGS INC.); MALLINCKRODT CARRIBEAN, INC.; MALLINCKRODT US POOL LLC; MNK 2011 LLC (F/K/A MALLINCKRODT INC.); LUDLOW LLC (F/K/A LUDLOW CORPORATION); CNS THERAPEUTICS, INC.; MALLINCKRODT ENTERPRISES HOLDINGS LLC (F/K/A MALLINCKRODT ENTERPRISES HOLDINGS, INC.); MALLINCKRODT ENTERPRISES LLC; MALLINCKRODT LLC; LAFAYETTE PHARMACEUTICALS LLC; LIEBEL-FLARSHEIM COMPANY LLC; MALLINCKRODT BRAND PHARMACEUTICALS LLC (F/K/A MALLINCKRODT BRAND PHARMACEUTICALS, INC.); MALLINCKRODT VETERINARY, INC.; MALLINCKRODT US HOLDINGS LLC; IMC EXPLORATION COMPANY; MEH, INC.; MALLINCKRODT HOSPITAL PRODUCTS IP UNLIMITED COMPANY (F/K/A MALLINCKRODT HOSPITAL PRODUCTS IP LIMITED); MALLINCKRODT ARD IP UNLIMITED COMPANY (F/K/A MALLINCKRODT ARD IP LIMITED); OCERA THERAPEUTICS LLC (F/K/A OCERA THERAPEUTICS, INC.); SPECGX LLC; STRATATECH CORPORATION; SUCAMPO PHARMA AMERICAS LLC; VTESSE LLC (F/K/A VTESSE INC.); MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED; MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY (F/K/A MALLINCKRODT PHARMA IP TRADING D.A.C.); INFACARE PHARMACEUTICAL CORPORATION; ST SHARED SERVICES LLC; IKARIA THERAPEUTICS LLC; INO THERAPEUTICS LLC
Reel/Frame 065609/0322 →
CHANGE OF NAME Recorded Apr 3, 2023
From: MALLINCKRODT NUCLEAR MEDICINE LLC
To: CURIUM US LLC
Reel/Frame 063240/0591 →
RELEASE OF SECURITY INTEREST Recorded Jan 31, 2017
From: DEUTSCHE BANK AG NEW YORK BRANCH
To: MALLINCKRODT NUCLEAR MEDICINE LLC
Reel/Frame 041131/0213 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 13, 2016
From: MALLINCKRODT LLC
To: MALLINCKRODT NUCLEAR MEDICINE LLC
Reel/Frame 039149/0234 →
SECURITY INTEREST Recorded Mar 19, 2014
From: MALLINCKRODT INTERNATIONAL FINANCE S.A.; MALLINCKRODT CB LLC; MALLINCKRODT FINANCE GMBH; MALLINCKRODT US HOLDINGS INC.; MALLINCKRODT CARIBBEAN, INC.; MALLINCKRODT US POOL LLC; MALLINCKRODT INC.; LUDLOW CORPORATION; CNS THERAPEUTICS, INC.; ENTERPRISES HOLDINGS, INC.; MALLINCKRODT ENTERPRISES LLC; MALLINCKRODT LLC; LAFAYETTE PHARMACEUTICALS LLC; LIEBEL-FLARSHEIM COMPANY LLC; MALLINCKRODT BRAND PHARMACEUTICALS, INC; MALLINCKRODT VETERINARY, INC.; MALLINCKRODT US HOLDINGS LLC; IMC EXPLORATION COMPANY; MEH, INC; MALLINCKRODT ENTERPRISES HOLDINGS, INC.
To: DEUTSCHE BANK AG NEW YORK BRANCH
Reel/Frame 032480/0001 →
CHANGE OF LEGAL ENTITY Recorded Aug 16, 2011
From: MALLINCKRODT INC.
To: MALLINCKRODT LLC
Reel/Frame 026754/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 19, 2009
From: HORTON, DUANE L.; SPETH, ANDREW D.
To: MALLINCKRODT INC.
Reel/Frame 022418/0742 →