TREATMENT OF BARRETT'S ESOPHAGUS USING PHOTODYNAMIC THERAPY
A method for treatment of Barrett's esophagus comprising the steps of: injecting HPPH in a physiologically compatible medium into a patient having Barrett's esophagus tissue to provide a dose level of 3 through 5 mg/m 2 of body surface area, waiting for a time period of 24 through 60 hours to permit preferential absorption of the HPPH into Barrett's esophagus tissue, and exposing the Barrett's esophagus tissue to light at a wavelength of about 670±5 nm at an energy of from about 75 to about 200 Joules/cm.
1 . A method for treatment of Barrett's esophagus comprising the steps of:
injecting HPPH in a physiologically compatible medium into a patient having Barrett's esophagus tissue to provide a dose level of 3 through 5 mg/m 2 of body surface area,
waiting for a time period of 24 through 60 hours to permit preferential absorption of the HPPH into Barrett's esophagus tissue, and
exposing the Barrett's esophagus tissue to light at a wavelength of about 670±5 nm at an energy of from about 75 to about 200 Joules.
2 . The method of claim 1 where the dose level of HPPH is 3.0 to 4.0 mg/m 2 .
3 . The method of claim 1 where the energy is from about 75 to about 150 Joules.
4 . The method of claim 1 where the waiting time is from about 24 to about 60 hours.