IP Library › Granted Patent US 8,012,929
Granted Patent B2
US 8,012,929 · App. 12/458,163 · Granted Sep 6, 2011

Peptides directed for diagnosis and treatment of amyloid-associated diseases

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,012,929
App. No.
12/458,163
Granted
Sep 6, 2011
Kind
B2
Abstract

Peptides having at least 2 amino acids and no more than 15 amino acids are provided. The peptides comprise amino acid sequence X-Y or Y-X, wherein X is an aromatic amino acid and Y is any amino acid other than glycine. Also provided are pharmaceutical compositions and kits including such peptides as well as methods using same for diagnosing and treating amyloid associated diseases.

Claims (3)

1. A method of treating an amyloid-associated disease in an individual in need thereof, the method comprising administering to the individual a therapeutically effective amount of a synthetic dipeptide set forth as (D-Trp-Aib), thereby treating the amyloid-associated disease in the individual.

2. The method of claim 1 , wherein said peptide is an active ingredient of a pharmaceutical composition which also includes a physiologically acceptable carrier.

3. The method of claim 1 , wherein the amyloid-associated disease is Alzheimer's disease.