Dermatological compositions and methods
Dermatological compositions (methods of making and using) that include one or more anesthetic agents and/or one or more anti-inflammatory agents and/or a combination of ammonium, sodium, and potassium salts, preferably of an alpha-hydroxy acid.
1. A dermatological composition comprising:
ammonium lactate in an amount of about 10% to about 15% by weight;
potassium lactate in an amount of about 3% to about 7% by weight; and
sodium lactate in an amount of about 3% to about 7% by weight;
wherein the composition has a pH of about 4.5 to about 5.5.
2. The dermatological composition of claim 1 further comprising at least one anti-foaming agent.
3. The dermatological composition of claim 1 further comprising at least one non-ionic surfactant selected from the group consisting of glyceryl stearate, PEG 100-stearate, polyoxyl-20-cetostearyl ether, glyceryl monooleate, glyceryl palmitosterate, self-emulsifying wax, polyoxyl-20-stearate, polyoxyl-40-stearate, polyoxyl-60-stearate, polyoxyl-80-stearate, polyoxyl-20-oleate, polyoxyl-40-oleate, polyoxyl-60-oleate, polyoxyl-80-oleate, polyoxyl-20-palmitate, polyoxyl-40-palmitate, polyoxyl-60-palmitate, polyoxyl-80-palmitate, emulsifying wax, laureth-2, laureth-4, laureth-6, laureth-8, and combinations thereof.
4. The dermatological composition of claim 1 further comprising at least one preservative selected from the group consisting of methyl paraben, ethyl paraben, propyl paraben, propyl paraben sodium salt, propyl paraben potassium salt, butyl paraben, and combinations thereof.
5. The dermatological composition of claim 4 wherein the preservative is present in the composition in an amount of about 0.02 wt.-% to about 1 wt.-%.
6. The dermatological composition of claim 1 further comprising at least one humectant selected from the group consisting of glycerin 99.5%, glycerin 95%, glycerin 85%, propylene glycol, butylene glycol, and combinations thereof.
7. The dermatological composition of claim 6 wherein the humectant is present in the composition in an amount of about 1 wt.-% to about 15 wt.-%.
8. The dermatological composition of claim 1 further comprising at least one anti-inflammatory agent.
9. The dermatological composition of claim 1 further comprising at least one anesthetic agent.
10. A dermatological composition comprising:
about 10 weight percent to about 15 weight percent of ammonium lactate;
about 3 weight percent to about 7 weight percent of sodium lactate;
about 3 weight percent to about 7 weight percent of potassium lactate;
about 1 weight percent to about 20 weight percent of light mineral oil;
about 2 weight percent to about 10 weight percent of emulsifying wax;
about 1 weight percent to about 5 weight percent of stearic acid;
about 0.01 weight percent to about 1 weight percent of propyl paraben;
about 1 weight percent to about 10 weight percent of glycerin;
about 0.0001 weight percent to about 10 weight percent of xanthan gum;
about 1 weight percent to about 15 weight percent of propylene glycol;
about 0.02 weight percent to about 1 weight percent of methyl paraben; and
about 30% and typically no greater than about 60% by weight of water;
wherein the composition has a pH of about 4.5 to about 5.5.
11. The dermatological composition of claim 1 which is odor-free.
12. The dermatological composition of claim 10 which is odor-free.
13. The dermatological composition of claim 10 further comprising an anesthetic, an anti-inflammatory agent, or a combination thereof.