IP Library Granted Patent US 7,918,009
Granted Patent B2
US 7,918,009 · App. 12/486,489 · Granted Apr 5, 2011

Methods of using radiopharmaceutical pigs

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Quick Facts
Patent No.
US 7,918,009
App. No.
12/486,489
Granted
Apr 5, 2011
Kind
B2
Abstract

A pharmaceutical pig is used to transport a syringe containing a liquid radiopharmaceutical from a radiopharmacy to a medical facility for administration to a patient. The pharmaceutical pig includes an elongate polymer cap that is removably attached to an elongate polymer base. The elongate polymer cap includes a cap shell that completely encloses a cap shielding element and the elongate polymer base includes a base shell that completely encloses a base shielding element. Preferably the polymer utilized for the cap shell and the base shell is polycarbonate resin, e.g., LEXAN®. An inner liner is not utilized and the cap shielding element and the base shielding element, which are preferably, but not necessarily, made of lead, are completely sealed and unexposed.

Claims (42)

1. A method of use for a radiopharmaceutical pig, the radiopharmaceutical pig comprising a base and a cap removably attachable to the base,

the base comprising:

a radiation-blocking base shielding element having an open end, a closed end, and at least one wall extending between the open and closed ends, the closed end and the at least one wall defining an interior of the base shielding element; and

a polymeric base shell that completely encloses an entirety of the base shielding element, the base shell defining a hollow section of the base; and the cap comprising:

a radiation-blocking cap shielding element having an open end, a closed end, and at least one wall extending between the open and closed ends, the closed end and the at least one wall defining an interior of the cap shielding element; and

a polymeric cap shell that completely encloses an entirety of the cap shielding element, the cap shell defining a hollow section of the cap,

the method comprising:

placing a syringe having a radiopharmaceutical therein into the hollow section of the base of the pig; and

attaching the cap of the pig to the base of the pig so that the cap shielding element and the base shielding element are in overlapping relationship with each other, and so that an inner base shell portion of the base shell and an inner cap shell portion of the cap shell are in overlapping relationship with each other to thereby enclose the syringe and the radiopharmaceutical in the syringe within the pig.

2. The method of claim 1 further comprising attaching a label to the syringe.

3. The method of claim 1 further comprising attaching a label to the pig.

4. The method of claim 1 further comprising placing the pig with the syringe and the radiopharmaceutical enclosed therein in a delivery container.

5. The method of claim 1 further comprising transporting the pig with the syringe and the radiopharmaceutical enclosed therein to a medical facility.

6. The method of claim 1 wherein the attaching comprises engaging threads on the cap of the pig with threads on the base of the pig.

7. The method of claim 6 wherein the engaging comprises rotating the cap no more than three hundred and sixty degrees (360°) with respect to the base.

8. The method of claim 6 wherein the engaging comprises rotating the cap no more than ninety degrees (90°) with respect to the base.

9. The method of any one of claims 6 - 8 further comprising at least one locking detent associated with the threads.

10. The method of claim 1 wherein the syringe comprises a barrel and a plunger, wherein the placing includes the barrel of the syringe being received in the hollow section of the base, and the attaching includes the plunger of the syringe being received in the hollow section of the cap.

11. The method of claim 1 wherein the cap shell and the base shell comprise polycarbonate resin.

12. The method of claim 1 wherein at least one of the base and the cap is elongate.

13. The method of claim 12 wherein both the base and the cap are elongate.

14. The method of claim 1 wherein an exterior of at least one of the base shell and the cap shell comprises a plurality of flat surfaces.

15. The method of claim 14 wherein the exterior of each of the base shell and the cap shell comprises a plurality of flat surfaces.

16. The method of claim 1 wherein the base shielding element comprises lead.

17. The method of claim 1 wherein the base shielding element is made of lead.

18. The method of claim 1 wherein the base shielding element comprises tungsten.

19. The method of claim 1 wherein the base shielding element is made of tungsten.

20. The method of claim 1 wherein the base shielding element comprises a metallic-filled polymer.

21. The method of claim 1 wherein the base shielding element is made of a metallic-filled polymer.

22. The method of claim 1 wherein the cap shielding element comprises lead.

23. The method of claim 1 wherein the cap shielding element is made of lead.

24. The method of claim 22 , wherein the base shielding element is made of lead.

25. The method of claim 1 wherein the cap shielding element comprises tungsten.

26. The method of claim 1 wherein the cap shielding element is made of tungsten.

27. The method of claim 1 wherein the cap shielding element comprises a metallic-filled polymer.

28. The method of claim 1 wherein the cap shielding element is made of a metallic-filled polymer.

29. The method of claim 1 wherein polymeric material is molded about the base shielding element to form the base shell.

30. The method of claim 1 wherein polymeric material is molded about the cap shielding element to form the cap shell.

31. The method of claim 1 wherein polymer material is molded about the base shielding element to form the base shell, and polymer material is molded about the cap shielding element to form the cap shell.

32. The method of claim 1 wherein the cap shell further comprises an annular flange adapted for face-to-face engagement with a portion of the base shell when the cap is attached to the base.

33. The method of claim 1 wherein the syringe comprises finger grips that are disposed between a portion of the base shell and a portion of the cap shell after the attaching.

34. The method of claim 1 wherein the hollow section of the base is devoid of a removable inner liner.

Assignments (2)
RELEASE OF PATENT SECURITY INTERESTS RECORDED AT REEL 032480, FRAME 0001 Recorded Nov 16, 2023
From: DEUTSCHE BANK AG NEW YORK BRANCH, AS COLLATERAL AGENT
To: THERAKOS, INC.; MALLINCKRODT INTERNATIONAL FINANCE S.A.; MALLINCKRODT CB LLC; MALLINCKRODT FINANCE GMBH; MALLINCKRODT US HOLDINGS LLC (F/K/A MALLINCKRODT US HOLDINGS INC.); MALLINCKRODT CARRIBEAN, INC.; MALLINCKRODT US POOL LLC; MNK 2011 LLC (F/K/A MALLINCKRODT INC.); LUDLOW LLC (F/K/A LUDLOW CORPORATION); CNS THERAPEUTICS, INC.; MALLINCKRODT ENTERPRISES HOLDINGS LLC (F/K/A MALLINCKRODT ENTERPRISES HOLDINGS, INC.); MALLINCKRODT ENTERPRISES LLC; MALLINCKRODT LLC; LAFAYETTE PHARMACEUTICALS LLC; LIEBEL-FLARSHEIM COMPANY LLC; MALLINCKRODT BRAND PHARMACEUTICALS LLC (F/K/A MALLINCKRODT BRAND PHARMACEUTICALS, INC.); MALLINCKRODT VETERINARY, INC.; MALLINCKRODT US HOLDINGS LLC; IMC EXPLORATION COMPANY; MEH, INC.; MALLINCKRODT HOSPITAL PRODUCTS IP UNLIMITED COMPANY (F/K/A MALLINCKRODT HOSPITAL PRODUCTS IP LIMITED); MALLINCKRODT ARD IP UNLIMITED COMPANY (F/K/A MALLINCKRODT ARD IP LIMITED); OCERA THERAPEUTICS LLC (F/K/A OCERA THERAPEUTICS, INC.); SPECGX LLC; STRATATECH CORPORATION; SUCAMPO PHARMA AMERICAS LLC; VTESSE LLC (F/K/A VTESSE INC.); MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED; MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY (F/K/A MALLINCKRODT PHARMA IP TRADING D.A.C.); INFACARE PHARMACEUTICAL CORPORATION; ST SHARED SERVICES LLC; IKARIA THERAPEUTICS LLC; INO THERAPEUTICS LLC
Reel/Frame 065609/0322 →
SECURITY INTEREST Recorded Mar 19, 2014
From: MALLINCKRODT INTERNATIONAL FINANCE S.A.; MALLINCKRODT CB LLC; MALLINCKRODT FINANCE GMBH; MALLINCKRODT US HOLDINGS INC.; MALLINCKRODT CARIBBEAN, INC.; MALLINCKRODT US POOL LLC; MALLINCKRODT INC.; LUDLOW CORPORATION; CNS THERAPEUTICS, INC.; ENTERPRISES HOLDINGS, INC.; MALLINCKRODT ENTERPRISES LLC; MALLINCKRODT LLC; LAFAYETTE PHARMACEUTICALS LLC; LIEBEL-FLARSHEIM COMPANY LLC; MALLINCKRODT BRAND PHARMACEUTICALS, INC; MALLINCKRODT VETERINARY, INC.; MALLINCKRODT US HOLDINGS LLC; IMC EXPLORATION COMPANY; MEH, INC; MALLINCKRODT ENTERPRISES HOLDINGS, INC.
To: DEUTSCHE BANK AG NEW YORK BRANCH
Reel/Frame 032480/0001 →