Granted Patent
B2
US 8,003,689 · App. 12/487,769 · Granted Aug 23, 2011
Metabolites of selective androgen receptor modulators and methods of use thereof
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Abstract
This invention provides metabolites of SARM compounds including inter alia glucuronidated metabolites and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, muscle wasting disease and/or disorder, a bone related disease and/or disorder, metabolic syndrome, diabetes and associated diseases, and others.
Claims (3)
1. An isolated metabolite of a selective androgen receptor modulator (SARM) compound
represented by the following structure:
2. The metabolite of claim 1 , wherein said metabolite is an optical isomer, pharmaceutically acceptable salt, or any combination thereof.
Assignments (3)
CHANGE OF NAME
Recorded Jul 4, 2019
From: GTX, INC.
To: ONCTERNAL THERAPEUTICS, INC
Reel/Frame 049679/0298 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INVENTOR'S NAME PREVIOUSLY RECORDED ON REEL 023088 FRAME 0121. ASSIGNOR(S) HEREBY CONFIRMS THE CORRECT SPELLING OF THE INVENTOR'S NAME IS VEVERKA, KAREN A..
Recorded Jan 26, 2010
From: VEVERKA, KAREN A.
To: GTX, INC.
Reel/Frame 023845/0756 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 12, 2009
From: VEVERKA, KAREN
To: GTX, INC.
Reel/Frame 023088/0121 →