IP Library Granted Patent US 8,178,492
Granted Patent B2
US 8,178,492 · App. 12/502,551 · Granted May 15, 2012

Methods and compositions for modulating adipocyte function

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Quick Facts
Patent No.
US 8,178,492
App. No.
12/502,551
Granted
May 15, 2012
Kind
B2
Abstract

Methods and compositions for treating obesity and related disorders. The methods include the use of BMP-2, -4, -6 and -7.

Claims (1)

1. A method of decreasing fat stores or weight in a subject, the method comprising identifying a subject in need of decreasing fat stores or weight, and administering to the subject a therapeutically effective amount of a composition consisting essentially of a bone morphogenetic protein 7 (BMP-7) in an amount sufficient to promote BAT differentiation in the subject and further comprising administering to the subject a FGF.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 22, 2011
From: BUTTE, ATUL
To: CHILDREN'S HOSPITAL BOSTON
Reel/Frame 026786/0734 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 22, 2011
From: KAHN, C. RONALD; TSENG, YU-HUA
To: JOSLIN DIABETES CENTER, INC.
Reel/Frame 026786/0742 →
CONFIRMATORY LICENSE Recorded Jun 10, 2011
From: CHILDREN'S HOSPITAL (BOSTON)
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 026421/0308 →