IP Library Granted Patent US 8,605,287
Granted Patent B2
US 8,605,287 · App. 12/506,766 · Granted Dec 10, 2013

Extended range imaging

Inventors: Tony H. Ko (San Jose, CA); Yonghua Zhao (Fremont, CA); David Huang (South Pasadena, CA)
Assignee: Optovue, Inc.
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Quick Facts
Patent No.
US 8,605,287
App. No.
12/506,766
Granted
Dec 10, 2013
Kind
B2
Abstract

An imager that can provide separated images corresponding to differing depths in a sample is presented. In accordance with some embodiments of the invention, an imager can include a light source; a sample arm that receives light from the light source, directs the light to a sample, and captures light returning from the sample; a modulation source that provides different modulations corresponding to differing imaging depths in the sample; a detector system to receive the captured light from the sample with the different modulations; and a processor that receives signals from the detector system and separates a plurality of images corresponding with the differing image depths in the sample.

Claims (28)

1. An imager, comprising:

a light source;

a sample arm that receives light from the light source, directs the light to a sample, and captures light returning from the sample;

a reference arm that provides different modulations corresponding to differing imaging depths in the sample, the reference arm comprising:

a plurality of reference paths being modulated to have different carrier frequencies corresponding to the differing imaging depths in the sample;

a first splitter/coupler forming the plurality of reference paths, wherein at least one reference path comprises optics coupled to a mirror and a modulator;

a detector system to receive the captured light from the sample and the different modulations provided by the reference arm; and

a processor that receives signals from the detector system and executes instructions to:

simultaneously obtain a plurality of overlapping images from the plurality of reference paths, the plurality of overlapping images corresponding to the differing imaging depths in the sample;

combine the simultaneously obtained plurality of overlapping images into a combined dataset, the combined dataset having a spatial frequency dimension and a transverse dimension;

perform a transform on the combined dataset along the transverse dimension for each value in the spatial frequency dimension to form a plurality of distributions along a carrier frequency dimension in the transformed dataset;

spectrally separate the plurality of distributions into a plurality of separated data based on a carrier frequency of each of the plurality of separated data; and

perform mathematical operations on each of the plurality of separated data to form a plurality of images corresponding with differing reference paths.

2. The imager of claim 1 , wherein a path length of the reference path correlates with an image depth of one of the plurality of images.

3. The imager of claim 1 , further comprising a second splitter/coupler coupled to the light source, the sample arm, the reference arm, and the detection system, wherein the splitter/coupler provides light to the sample arm and the reference arm, receives light from the sample arm and the reference arm, and provides combined light from the sample arm and the reference arm to the detector system.

4. The imager of claim 1 , wherein the processor provides control signals to the reference arm and the sample arm.

5. The imager of claim 1 , wherein the light source includes a broad band source and the detection system can include a spectrometer.

6. The imager of claim 1 , wherein the light source includes a swept laser source and the detection system can include a photodiode detector system.

7. The imager of claim 1 , wherein the reference arm further comprises a polarizer.

8. A method of separating simultaneously obtained images in an OCT imager, comprising:

simultaneously obtaining a plurality of overlapping images using the OCT imager from a plurality of reference paths that each provide different modulations to induce different carrier frequencies corresponding to differing imaging depths in a sample;

combining the simultaneously obtained plurality of overlapping images into a combined dataset, the combined dataset having a spatial frequency dimension and a transverse dimension;

performing a transform on the combined dataset along the transverse dimension for each value in the spatial frequency dimension to form a plurality of distributions along a carrier frequency dimension in the transformed dataset;

spectrally separating the plurality of distributions into a plurality of separated data based on a carrier frequency of each of the plurality of separated data; and

performing mathematical operations on each of the plurality of separated data to generate separate images from the plurality of overlapping images.

9. The method of claim 8 , wherein the transform is a Fourier transform.

10. The method of claim 8 , wherein performing mathematical operations includes performing an inverse Fourier transform in a transverse direction on the separated data; and

performing the inverse Fourier transform in a frequency direction on the separated data.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Jul 28, 2023
From: OPTOVUE, INC.
To: SOCIÉTÉ GÉNÉRALE, AS SECURITY AGENT
Reel/Frame 064420/0570 →
NOTICE OF SECURITY INTEREST - PATENTS Recorded Jan 3, 2022
From: OPTOVUE, INC.
To: SOCIÉTÉ GÉNÉRALE, AS SECURITY AGENT
Reel/Frame 058603/0315 →
RELEASE OF SECURITY INTEREST Recorded May 30, 2014
From: SILICON VALLEY BANK
To: OPTOVUE, INC.
Reel/Frame 033063/0641 →
SECURITY AGREEMENT Recorded Oct 11, 2012
From: OPTOVUE, INC.
To: SILICON VALLEY BANK
Reel/Frame 029117/0574 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 8, 2010
From: HUANG, DAVID
To: OPTOVUE, INC.
Reel/Frame 024204/0484 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 31, 2009
From: KO, TONY; ZHAO, YONGHUA
To: OPTOVUE, INC.
Reel/Frame 023173/0954 →
Continuity (2)
Provisional Application 61135613 · Jul 21, 2008
Related Publication 20100033727A1 · Feb 11, 2010