Systems and methods for filling medical device lumen
View Patent ↗The invention relates to systems and methods for filling a medical device with an active agent composition. In an embodiment, the invention includes a method for filling a medical device with an active agent composition. The method can include applying the active agent composition to the outside surface of the medical device, the medical device comprising a housing defining a lumen and a plurality of apertures. The method can also include contacting a surface of a press member against the outside surface of the medical device thereby pushing the active agent composition through the apertures and into the lumen of the medical device. Other embodiments are also included herein.
1. A method of loading a medical device with an active agent, the method comprising:
disposing an active agent in an interior volume of a fluidization chamber, wherein the interior volume of the fluidization chamber is in fluid communication with a first conduit and a second conduit;
pumping air from an air supply source through the first conduit into the interior volume of the fluidization chamber;
mixing the active agent with the air in the fluidization chamber to form a mixture;
directing the active agent and air mixture into one or more apertures of a medical device via the second conduit, wherein the medical device comprises an outside surface and a lumen and one or more apertures connect the lumen to the outside surface; and
depositing the active agent within the lumen of the medical device.
2. The method of claim 1 , wherein pumping the air into the interior volume of the fluidization chamber causes turbulence within the interior volume of the fluidization chamber to mix the active agent with the air.
3. The method of claim 1 , wherein some of the apertures of the medical device are at least partially occluded.
4. The method of claim 3 , wherein some of the occluded apertures block passage of the active agent particles into the lumen while allowing air to flow through the lumen.
5. The method of claim 3 , wherein one or more apertures are occluded by a porous sheath or mesh structure.