IP Library Granted Patent US 11,000,484
Granted Patent B2
US 11,000,484 · App. 12/508,959 · Granted May 11, 2021

Methods for diagnosing and treating a heart condition in a patient

Inventor: David H. Fine (Cocoa, FL)
Assignee: Vero Biotech LLC
A61K31/04G01N33/6893G01N2800/324
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Quick Facts
Patent No.
US 11,000,484
App. No.
12/508,959
Granted
May 11, 2021
Kind
B2
Abstract

Various methods for diagnosing and treating heart conditions are disclosed herein. According to one method, nitric oxide is delivered to a patient's lungs when the patient has one or more symptoms of a heart condition. The patient is diagnosed as suffering from a heart condition when a symptom of a heart condition subsides after nitric oxide delivery.

Claims (13)

1. A method, comprising:

identifying a chest pain consistent with a myocardial infarction in a patient;

continuously delivering at least 20 ppm of nitric oxide to the patient's lungs for 5 to 10 seconds via a health care kit, the health care kit including a liquid N 2 O 4 source, connected to an air pump supplying nitric oxide gas by forcing air over the liquid N 2 O 4 source to introduce gaseous NO 2 into the air so that the air containing the introduced gaseous NO 2 contacts a surface active material that converts the gaseous NO 2 in the air to gaseous nitric oxide, and a cannula which delivers the gaseous nitric oxide to the patient's lungs in the absence of NO 2 ;

determining that the chest pain abated while the nitric oxide is being delivered to the patient's lungs

ceasing delivery of nitric oxide to the patient; and

identifying a return of the chest pain after ceasing delivery of nitric oxide to the patient's lungs, the patient being treated for the myocardial infarction based on the chest pain abating while the nitric oxide is being delivered and returning after ceasing delivery of the nitric oxide.

2. The method of claim 1 , wherein nitric oxide is delivered with air or oxygen enriched air.

3. The method of claim 1 , wherein the chest pain is accompanied by shortness of breath, nausea, sweating, lightheadedness, or any combination thereof.

4. The method of claim 1 , wherein the nitric oxide is delivered during a first time period before identifying the return of the chest pain, the method further comprising:

delivering nitric oxide during a second time period after identifying the return of the chest pain.

5. The method of claim 1 , wherein determining that the chest pain abated occurs is less than 100 seconds after delivering nitric oxide begins.

6. The method of claim 1 , wherein identifying the return of the chest pain occurs less than 100 seconds after ceasing delivery of nitric oxide.

7. The method of claim 1 , wherein a period of time between identifying a chest pain consistent with myocardial infarction and an initiation of the delivery of nitric oxide is less than 10 hours.

Assignments (6)
SECURITY INTEREST Recorded Mar 16, 2026
From: VERO BIOTECH INC.
To: SYMBIOTIC CAPITAL AGENCY LLC, AS COLLATERAL AGENT
Reel/Frame 075117/0935 →
TERMINATION AND RELEASE OF INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jan 3, 2024
From: RUNWAY GROWTH FINANCE CORP (F/K/A RUNWAY GROWTH CREDIT FUND INC.)
To: VERO BIOTECH INC. (F/K/A VERO BIOTECH LLC)
Reel/Frame 066186/0611 →
CHANGE OF NAME Recorded Feb 14, 2022
From: VERO BIOTECH LLC
To: VERO BIOTECH INC.
Reel/Frame 059085/0418 →
SECURITY INTEREST Recorded Dec 29, 2020
From: VERO BIOTECH LLC
To: RUNWAY GROWTH CREDIT FUND INC.
Reel/Frame 054866/0589 →
CHANGE OF NAME Recorded Aug 7, 2018
From: GENO LLC
To: VERO BIOTECH LLC
Reel/Frame 048173/0247 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 28, 2013
From: FINE, DAVID H.
To: GENO LLC
Reel/Frame 031486/0103 →
Cited By (2)
US 12,544,527 US 12,605,520