Ingestible electronic capsule and in vivo drug delivery or diagnostic system

1. An ingestible electronic capsule for introduction into a bodily lumen, comprising:

a housing;

a continuous flex foil formed of a uniform material and having a first portion extending generally in a longitudinal direction, the flex foil further having a second portion that extends from the first portion at an angle relative to the longitudinal direction;

an electrically conducting layer integrated into the second portion;

a plurality of electronic components disposed directly on the flex foil and spaced from each other along the longitudinal direction on the first portion, the continuous flex foil being bent along at least one bend line disposed in the lateral direction between adjacent electronic components to form a bent flex foil and the second portion being bent relative to the first portion;

a reservoir sealed relative to the first portion of the housing, the reservoir containing a drug for expulsion from the capsule via a dispensing hole; and

a release mechanism movable to empty the drug through the dispensing hole, the release mechanism being electrically connected to at least one of the plurality of electronic components formed on the flex foil.

2. The ingestible electronic capsule according to claim 1 , wherein the electrically conducting layer is an antenna.

3. The ingestible electronic capsule according to claim 2 , wherein the antenna is wrapped around a remainder of the flex foil.

4. The ingestible electronic capsule according to claim 1 , wherein the at least one electronic component is attached to the flex foil with a solder bump.

5. The ingestible electronic capsule according to claim 4 , wherein at least part of remaining open space between the flex foil and the at least one electronic component is filled with a moldable resin.

6. The ingestible electronic capsule according to claim 1 , wherein a power supply unit is mounted on the flex foil with a conducting adhesive.

7. The ingestible electronic capsule according to claim 1 , wherein the flex foil is bended along at least one bending line.

8. The ingestible electronic capsule according to claim 1 , wherein the ingestible electronic capsule comprises a system in package with a microprocessor a transceiver, a sensor and a passive electronic device.

9. The ingestible electronic capsule according to claim 1 , wherein the release mechanism is a movable piston for emptying the drug reservoir, which movable piston is electrically and mechanically connected to the flex foil.

10. In vivo drug delivery or diagnostic system comprising an ingestible electronic capsule according to claim 1 and an external device arranged to communicate with the at least one electronic component.

11. The ingestible capsule of claim 1 , further comprising a socket configured to receive a plug, wherein the flex foil includes a side arm electrically connecting the socket to the flex foil.

12. The ingestible capsule of claim 11 , wherein the side arm is removable.

13. The ingestible capsule of claim 9 , wherein the flex foil partially unfolds along at least one folding line when the movable piston is actuated to empty the drug reservoir.

14. The ingestible capsule of claim 1 , wherein the flex foil comprises a circuit board and the electronic components are formed directly on the circuit board without a rigid circuit board.

15. An ingestible capsule comprising:

a housing defining one or more compartments; and

a bent flex foil disposed in one of the compartments, the bent flex foil comprising a plurality of electronic components disposed directly on a continuous, flexible circuit board and further comprising an antenna formed as an oblique extension of the flexible circuit board, wherein the flexible circuit board is bent along bend lines disposed between the plurality of electronic components and the antenna is bent relative to the remainder of the flexible circuit board.

16. The ingestible capsule of claim 15 , wherein each of the plurality of electronic components is free of a rigid circuit board.

17. The ingestible capsule of claim 15 , wherein the antenna comprises an electrically conducting layer integrated into the flexible circuit board.

18. The ingestible capsule of claim 15 , wherein at least one of the plurality of electronic components is attached to the flexible circuit board using a solder bump.

19. The ingestible capsule of claim 15 , wherein a moldable resin fixes at least one of the plurality of electronic components to the flexible circuit board.

20. The ingestible capsule of claim 15 , wherein the electronic components comprise at least one of a capacitor and a coil.