Use of tellurium compounds for the treatment of actinic keratosis
View Patent ↗Methods for treating skin conditions such as basal cell carcinoma and/or actinic keratosis are provided, which are effected by administering a pharmaceutically effective amount of a tellurium-containing compound. A pharmaceutical composition for treatment of skin conditions such as basal cell carcinoma an/or actinic keratosis is also provided.
1. A method of treating actinic keratosis in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of at least one tellurium-containing compound selected from the group consisting of tellurium dioxide (TeO 2 ), a complex of TeO 2 , a compound having general Formula I:
and a compound having general Formula II:
wherein:
Y is selected from the group consisting of ammonium, phosphonium, potassium, sodium and lithium; and
X is a halogen atom.
2. The method of claim 1 , wherein X is chloro.
3. The method of claim 2 , wherein Y is ammonium.
4. The method of claim 1 , wherein said administering is effected systemically.
5. The method of claim 1 , wherein said administering is effected topically.
6. The method of claim 1 , wherein said tellurium-containing compound is ammonium trichloro(dioxyethylene-O,O′)tellurate.