Randomly oriented, FGF-2-modified nanofiber device for use in spinal cord repair
View Patent ↗The invention relates to a device composed of a plurality of strips of randomly oriented nanofibers, wherein said strips are arranged along their longitudinal axes. In addition, the surface of the device's nanofibers are covalently modified with fibroblast growth factor-2. A method for using the instant device for facilitating axonal regeneration in spinal cord injury is also provided.
1. A device comprising a plurality of strips of randomly oriented nanofibers, wherein said strips are arranged along their longitudinal axes and the surface of the nanofibers are covalently modified with fibroblast growth factor-2, and wherein said device facilitates axonal regeneration following spinal cord injury.
2. A method for facilitating axonal regeneration following spinal cord injury comprising contacting an injured spinal cord with the device of claim 1 thereby facilitating axonal regeneration of the injured spinal cord.