Device for washing and hybridization of biochips
View Patent ↗A device for biochip hybridization or washing is provided, which comprises a carousel ( 12 ), a translational movement controller, a revolving movement controller, and optionally a heating chamber ( 13 ). The revolving movement controller controls the revolving movement of the carousel and allows it to move in a wobbling fashion, allowing liquid movement of the hybridization or washing boxes ( 11 ) during hybridization and/or washing of biochips on the carousel. The translational movement controller brings the carousel back to horizontal position once the revolving movement controller stops, thereby ensures that the liquid do not spill out. The heating chamber circulates hot air within the device, thereby ensures that the hybridization and washing in a thermostatic condition.
1. A device for biochip hybridization or washing, comprising:
a) a carousel;
b) a translational movement controller comprising a base, a sliding rail on the base, a slide block on the sliding rail, a translational movement motor, and a driving assembly that couples the motor to the slide block; and
c) a revolving movement controller comprising a base, a revolving movement motor, an eccentric block coupled to the revolving movement motor, a pendulum shaft comprising an upper shaft and a lower shaft connected to each other via a bearing, a rotary disk fixed on the upper shaft and a plurality of springs that connect the rotary disk to the base and pulls the rotary disk from rotating, and a photoelectric sensor, wherein the lower shaft is connected to the eccentric block and the upper shaft is connected to the carousel,
wherein the revolving movement controller is placed on the slide block of the translational movement controller, and
wherein the photoelectric sensor senses the stop of the revolving movement controller and triggers the start of the translational movement controller, thereby brings the carousel to a horizontal position.
2. The device of claim 1 , further comprising a heating chamber.
3. The device of claim 2 , wherein the heating chamber comprises a temperature sensor.
4. The device of claim 2 , wherein the heating chamber comprises a heater, a fan, and a conduit, wherein the fan, the conduit and the space where the carousel resides form a closed hot air circulating pathway.
5. The device of claim 4 , wherein the heating chamber comprises at least two air circulating fans and at least two heat exchanging fans.
6. The device of claim 5 , wherein the heating chamber comprises at least two air conduits.