Pyrrolo[4,3,2-de]quinolin-8-amine compounds and methods of their preparation and use
View Patent ↗The present invention relates to compounds of formula I: methods of their use, processes for their preparation and isolated actinomycetes strains capable of preparing pyrrolo[4,3,2-de]quinolin-8-amine compounds.
1. The compound (E)-N-(8-amino-4-(3-methoxyacryloyl)pyrrolo[4,3,2-de]quinolin-6-yl)isobutyramide, or a tautomer, stereoisomer or pharmaceutically acceptable salt thereof.
2. A pharmaceutical composition comprising the compound of claim 1 or a tautomer, stereoisomer or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
3. The pharmaceutical composition of claim 2 , wherein said compound, tautomer, stereoisomer or pharmaceutically acceptable salt thereof is present in sufficient amount to treat prostate cancer or breast cancer in an patient.