IP Library Granted Patent US 8,701,657
Granted Patent B2
US 8,701,657 · App. 12/541,141 · Granted Apr 22, 2014

Systems for generating nitric oxide

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Quick Facts
Patent No.
US 8,701,657
App. No.
12/541,141
Granted
Apr 22, 2014
Kind
B2
Abstract

In one aspect, a system for delivering nitric oxide to a patient can include a first gas source including nitrogen dioxide mixed in air or oxygen, a second gas source supplying compressed air, a ventilator coupled to the first and second gas sources, where the ventilator can be resistant to nitrogen dioxide, and where the ventilator provides a gas flow having a proper amount of nitrogen dioxide, one or more conversion devices operably coupled to the ventilator, where the conversion devices covert nitrogen dioxide into nitric oxide, and a patient interface operably coupled to the conversion devices, where the patient interface delivers nitric oxide to the patient.

Claims (17)

1. A system for delivering nitric oxide to a patient, comprising:

a first gas source including nitrogen dioxide premixed in air or oxygen;

a second gas source supplying compressed air;

a ventilator coupled to the first and second gas sources;

a mixing valve which is connected to both the first gas source and the second gas source downstream of both the first gas source and the second gas source, wherein the mixing valve is resistant to NO 2 gases;

one or more conversion devices operably coupled to the ventilator, wherein the one or more conversion devices include

an inlet,

a chamber containing a matrix, wherein the matrix is positioned within the chamber and a space between the chamber and the matrix, and

a diverter positioned between the inlet and the chamber, wherein the diverter is configured to direct a gas flow to the space between the chamber and the matrix, and

wherein the one or more conversion devices convert nitrogen dioxide into nitric oxide; and

a patient interface operably coupled to the one or more conversion devices, wherein the patient interface delivers nitric oxide to the patient.

2. The system of claim 1 , further comprising a third gas source supplying compressed oxygen, wherein the third gas source is in communication with the ventilator.

3. The system of claim 1 , further comprising a humidifier positioned between the ventilator and the one or more conversion devices.

4. The system of claim 1 , comprising a first conversion device of the one or more conversion devices, wherein a humidifier is integral with the first conversion device.

5. The system of claim 1 , comprising a first conversion device of the one or more conversion devices and a second conversion device of the one or more conversion devices, wherein a humidifier is integral with the second conversion device.

6. The system of claim 1 , comprising a first conversion device of the one or more conversion devices, a second conversion device of the one or more conversion devices and a humidifier, wherein the humidifier is positioned between the first conversion device and the patient interface and before the second conversion device.

7. The system of claim 1 , wherein the mixing valve is within the ventilator.

Assignments (6)
SECURITY INTEREST Recorded Mar 16, 2026
From: VERO BIOTECH INC.
To: SYMBIOTIC CAPITAL AGENCY LLC, AS COLLATERAL AGENT
Reel/Frame 075117/0935 →
TERMINATION AND RELEASE OF INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jan 3, 2024
From: RUNWAY GROWTH FINANCE CORP (F/K/A RUNWAY GROWTH CREDIT FUND INC.)
To: VERO BIOTECH INC. (F/K/A VERO BIOTECH LLC)
Reel/Frame 066186/0611 →
CHANGE OF NAME Recorded Feb 14, 2022
From: VERO BIOTECH LLC
To: VERO BIOTECH INC.
Reel/Frame 059085/0418 →
SECURITY INTEREST Recorded Dec 29, 2020
From: VERO BIOTECH LLC
To: RUNWAY GROWTH CREDIT FUND INC.
Reel/Frame 054866/0589 →
CHANGE OF NAME Recorded Jun 6, 2018
From: GENO LLC
To: VERO BIOTECH LLC
Reel/Frame 046304/0855 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 3, 2009
From: FINE, DAVID H.; VASQUEZ, GREGORY; JOHNSON, BRYAN
To: GENO LLC
Reel/Frame 023461/0172 →