IP Library Granted Patent US 9,125,982
Granted Patent B2
US 9,125,982 · App. 12/556,184 · Granted Sep 8, 2015

Methods and systems for providing metered doses of a compound to an individual

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Quick Facts
Patent No.
US 9,125,982
App. No.
12/556,184
Granted
Sep 8, 2015
Kind
B2
Abstract

An implantable pump for providing metered doses of a compound to an individual is described. The implantable pump includes a chamber for storing an individual dose of the compound, an inlet valve fluidly coupled to the chamber for controlling a flow of the compound into the chamber, and an outlet valve fluidly coupled to the chamber for controlling a flow of the compound out of the chamber and into the individual. The pump includes an inlet valve driver circuit operable for opening and closing the inlet valve, and an outlet valve driver circuit operable for opening and closing the outlet valve. A battery and a charging circuit that includes a capacitor are included in the implantable pump. The charging circuit is operatively coupled to the battery for charging of the capacitor. The charged capacitor is operable for supplying power to the valve driver circuits.

Claims (53)

1. An implantable pump for providing metered doses of a compound to an individual, said implantable pump comprising:

a chamber for storing an individual dose of the compound;

an inlet valve fluidly coupled to said chamber for controlling a flow of the compound into said chamber, wherein said inlet valve is an electrically actuated valve;

an inlet valve driver circuit electrically coupled to said inlet valve and operable for opening and closing said inlet valve;

an outlet valve fluidly coupled to said chamber for controlling a flow of the compound out of said chamber and into the individual, wherein said outlet valve is an electrically actuated valve;

an outlet valve driver circuit electrically coupled to said outlet valve and operable for opening and closing said outlet valve;

a battery;

a charging circuit comprising a capacitor, said charging circuit operatively coupled to said battery for charging of said capacitor, said capacitor, when charged, operable for supplying power to said inlet valve driver circuit and said outlet valve driver circuit; and

an interlock circuit, wherein said interlock circuit is operable to prevent said inlet valve driver circuit from electrically actuating the inlet valve to open the inlet valve and to prevent said outlet valve driver circuit from electrically actuating the outlet valve to open the outlet valve during the same time interval.

2. An implantable pump according to claim 1 further comprising a programmable device programmed to:

cause said inlet valve driver circuit to open said inlet valve;

cause said inlet valve driver circuit to close said inlet valve after a predetermined length of time has passed since said inlet valve driver circuit caused said inlet valve to open;

cause said outlet valve driver circuit to open said outlet valve a predetermined length of time after causing said inlet valve driver circuit to close said inlet valve; and

cause said outlet valve driver circuit to close said outlet valve after a predetermined length of time has passed since said outlet valve driver circuit caused said outlet valve to open.

3. An implantable pump according to claim 2 wherein said programmable device comprises a wireless interface, said programmable device is reprogrammable via instructions received via said wireless interface.

4. An implantable pump according to claim 3 wherein the instructions include:

instructions to be executed by said programmable device that set an amount of time said inlet valve driver circuit causes said inlet valve to be open;

instructions to be executed by said programmable device that set an amount of time said outlet valve driver circuit causes said outlet valve to be open;

instructions to be executed by said programmable device that set an amount of time between closure of said inlet valve and opening of said outlet valve; and

instructions to be executed by said programmable device that set an amount of time between closure of said outlet valve and opening of said inlet valve.

5. An implantable pump according to claim 1 wherein the interlock circuit is operable to prevent said inlet valve driver circuit and said outlet valve driver circuit from being actuated during a time interval when said battery is charging said capacitor.

6. An implantable pump according to claim 1 wherein said charging circuit is operable to charge said capacitor to a voltage that is greater than a voltage associated with said battery.

7. An implantable pump according to claim 6 wherein the voltage level to which said capacitor is charged is a voltage level compatible with operation of said inlet valve driver circuit and said outlet valve driver circuit.

8. An implantable pump according to claim 1 wherein said charging circuit is operable to prevent said battery from directly supplying current to said inlet valve driver circuit and said outlet valve driver circuit.

9. A method for operating an implantable pump, the implantable pump including an inlet valve, an outlet valve, an inlet valve driver circuit, an outlet valve driver circuit, a charging circuit that includes a storage capacitor for supplying a voltage to the valve driver circuits, an interlock circuit, and a battery for operating the charging circuit, said method comprising:

charging the capacitor in the charging circuit using the battery;

operating the inlet valve driver circuit, using the charged capacitor, to electrically open the inlet valve, wherein said inlet valve is an electrically actuated valve;

maintaining the inlet valve in an open configuration to allow a compound stored in a reservoir to pass into an accumulator;

operating the inlet valve driver circuit to electrically close the inlet valve;

charging the capacitor in the charging circuit using the battery;

operating the outlet valve driver circuit, using the charged capacitor, to electrically open the outlet valve, wherein said outlet valve is an electrically actuated valve;

maintaining the outlet valve in an open configuration to allow a compound stored in the accumulator to pass into a user of the implantable pump;

operating the outlet valve driver circuit to electrically close the outlet valve; and

preventing the inlet valve driver circuit from using the charged capacitor to electrically open the inlet valve and preventing the outlet valve driver circuit from using the charged capacitor to electrically open the outlet valve during the same time interval using the interlock circuit.

10. A method according to claim 9 wherein:

operating the inlet valve driver circuit to close the inlet valve comprises causing the inlet valve driver circuit to close the inlet valve after a predetermined length of time has passed since the inlet valve driver circuit caused the inlet valve to open; and

operating the outlet valve driver circuit to close the outlet valve comprises causing the outlet valve driver circuit to close the outlet valve after a predetermined length of time has passed since the outlet valve driver circuit caused the outlet valve to open.

11. A method according to claim 9 further comprising preventing at least one of the inlet valve driver circuit and the outlet valve driver circuit from being actuated during a time interval when the battery is charging the capacitor through the charging circuit.

12. A method according to claim 9 wherein charging the capacitor in the charging circuit using the battery comprises increasing a voltage associated with the battery for storage within the capacitor.

13. A method according to claim 9 wherein charging the capacitor in the charging circuit using the battery comprises preventing the battery from directly supplying current to the valve driver circuits.

14. A circuit for controlling operation of an electrically actuated inlet valve and an electrically actuated outlet valve of an implantable pump, the electrically actuated inlet valve operable to allow a metered dose of a compound to pass from a reservoir to an accumulator, the electrically actuated outlet valve operable to allow the metered dose to pass from the accumulator into a user of the implantable pump, said circuit comprising:

an inlet valve driver circuit operable for opening and closing the electrically actuated inlet valve;

an outlet valve driver circuit operable for opening and closing the electrically actuated outlet valve;

a battery;

a charging circuit comprising a capacitor, said charging circuit operatively coupled to said battery for charging of said capacitor, said capacitor operable for supplying power to said inlet valve driver circuit and said outlet valve driver circuit and further operable for preventing said battery from directly supplying current to said inlet valve driver circuit and said outlet valve driver circuit; and

an interlock circuit operable to prevent said inlet valve driver circuit from electrically actuating the inlet valve to open the inlet valve and to prevent the outlet valve driver circuit from electrically actuating the outlet valve to open the outlet valve during the same time interval.

15. A circuit according to claim 14 wherein said charging circuit is operable to increase a voltage associated with said battery for storage within said capacitor.

16. A circuit according to claim 14 further comprising a programmable device operable to:

execute instructions that control an amount of time said inlet valve driver circuit causes the electrically actuated inlet valve to be open;

execute instructions that control an amount of time said outlet valve driver circuit causes the electrically actuated outlet valve to be open;

execute instructions that control an amount of time between operating said inlet valve driver circuit to close the electrically actuated inlet valve and operating said outlet valve driver circuit to open the electrically actuated outlet valve; and

execute instructions that control an amount of time between operating said outlet valve driver circuit to close the electrically actuated outlet valve and operating said inlet valve driver circuit to open the electrically actuated inlet valve.

17. A circuit according to claim 14 further comprising a programmable device operable to control operation of said inlet valve driver circuit, said outlet valve driver circuit, and said charging circuit, said programmable device comprising a wireless interface, said programmable device reprogrammable based on instructions received at said wireless interface.

Assignments (13)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 20, 2025
From: FLO (ABC), LLC
To: ALGORITHM SCIENCES, INC.
Reel/Frame 070271/0187 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 14, 2024
From: ALGORITHM SCIENCES, INC.
To: INFUSYN THERAPEUTICS, LLC
Reel/Frame 069258/0851 →
RELEASE OF SECURITY INTEREST Recorded Feb 17, 2023
From: SILICON VALLEY BANK
To: FLOWONIX MEDICAL INCORPORATED
Reel/Frame 062733/0192 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 10, 2023
From: FLOWONIX MEDICAL INCORPORATED
To: FLO(ABC), LLC
Reel/Frame 062326/0374 →
SECURITY INTEREST Recorded May 6, 2022
From: FLOWONIX MEDICAL INCORPORATED
To: SWK FUNDING LLC
Reel/Frame 059840/0049 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Feb 12, 2021
From: FLOWONIX MEDICAL INCORPORATED
To: SILICON VALLEY BANK
Reel/Frame 055297/0961 →
TERMINATION AND RELEASE OF INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jan 13, 2021
From: HERCULES CAPITAL, INC.
To: FLOWONIX MEDICAL INCORPORATED
Reel/Frame 054980/0672 →
TERMINATION AND RELEASE OF INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Dec 30, 2020
From: PUMPERNICKEL HOLDINGS, LLC
To: FLOWONIX MEDICAL INCORPORATED
Reel/Frame 054895/0943 →
SECURITY INTEREST Recorded Sep 21, 2018
From: FLOWONIX MEDICAL INCORPORATED
To: HERCULES CAPITAL, INC., AS AGENT
Reel/Frame 046944/0066 →
SECURITY INTEREST Recorded May 22, 2017
From: FLOWONIX MEDICAL INCORPORATED
To: PUMPERNICKEL HOLDINGS LLC
Reel/Frame 042448/0122 →
CHANGE OF NAME Recorded Apr 10, 2012
From: MEDASYS INCORPORATED
To: FLOWONIX MEDICAL INCORPORATED
Reel/Frame 028023/0921 →
CHANGE OF NAME Recorded Jun 15, 2010
From: INSET TECHNOLOGIES INCORPORATED
To: MEDASYS INCORPORATED
Reel/Frame 024537/0791 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 9, 2009
From: FREY, DANIEL JOHN
To: INSET TECHNOLOGIES INCORPORATED
Reel/Frame 023207/0064 →