IP Library Granted Patent US 8,227,761
Granted Patent B2
US 8,227,761 · App. 12/561,949 · Granted Jul 24, 2012

True coincidence summing correction and total efficiency computation for radionuclide spectroscopy analysis

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Quick Facts
Patent No.
US 8,227,761
App. No.
12/561,949
Granted
Jul 24, 2012
Kind
B2
Abstract

A method, system, and software for calculating the true coincidence summing effects for radionuclide spectroscopy analysis. A set of equations which can be implemented with a stored computer program performs calculations to correct the spectroscopic analysis data for gamma-gamma coincidence events, gamma-X-ray coincidence events, as well as gamma-annihilation photon coincidence events. The net gamma-ray, KX-ray and annihilation photon summing-out probabilities for the analytic gamma-ray is the total summing-out probability from all gamma-ray summing-out chains subtracted by the total summing-out probability from all gamma-ray sub-cascade chains involving the analytic gamma-ray. A total efficiency calculation is performed to eliminate the need for using radioactive sources to create summing specific calibration measurements and for increased accuracy.

Claims (37)

1. A spectroscopy analysis method comprising:

obtaining output data from at least one photon detection device;

step for calculating, with a processing device, a gamma-gamma coincidence summing correction factor and an X-ray coincidence summing correction factor for multiple coincident gamma and X-ray detections;

applying the X-ray coincidence summing correction factor to the gamma-gamma coincidence summing correction factor to generate corrected full energy peak measurement data; and

transforming the corrected full energy peak measurement data to a visual representation for presentation on a display device for operator review.

2. The spectroscopy analysis method of claim 1 , further comprising:

step for calculating, with the processing device, an annihilation photon coincidence summing correction factor for coincidences between gamma and annihilation photon detections; and

applying the annihilation photon coincidence summing correction factor to the gamma-gamma coincidence summing correction factor to generate corrected full energy peak measurement data.

3. The spectroscopy analysis method of claim 2 further comprising:

applying the X-ray coincidence summing correction factor and annihilation photon coincidence summing correction factor simultaneously to the gamma-gamma coincidence summing correction factor to generate corrected full energy peak measurement data.

4. The spectroscopy analysis method of claim 2 further comprising:

using a total gamma efficiency in the computation of the gamma-gamma, X-ray-gamma, and the annihilation photon-gamma coincidence summing correction factors.

5. A computer readable medium tangibly embodying machine-readable instructions executable by a computer processor to perform a spectroscopy analysis method instructions comprising:

obtaining output data from at least one photon detection device;

step for calculating a gamma-gamma coincidence summing correction factor and an X-ray coincidence summing correction factor for multiple coincident gamma and X-ray detections;

applying the X-ray coincidence summing correction factor to the gamma-gamma coincidence summing correction factor to generate corrected full energy peak measurement data; and

transforming the corrected full energy peak measurement data to a visual representation for presentation on a display device for operator review.

6. The computer readable medium of claim 5 , the instructions further comprising:

step for calculating an annihilation photon coincidence summing correction factor for coincidences between gamma and annihilation photon detections; and

applying the annihilation photon coincidence summing correction factor to the gamma-gamma coincidence summing correction factor to generate corrected full energy peak measurement data.

7. The computer readable medium of claim 6 , the instructions further comprising:

applying the X-ray coincidence summing correction factor and annihilation photon coincidence summing correction factor simultaneously to the gamma-gamma coincidence summing correction factor to generate corrected full energy peak measurement data.

8. The computer readable medium of claim 6 , the instructions further comprising:

using a total gamma efficiency in the computation of the gamma-gamma, X-ray-gamma, and the annihilation photon-gamma coincidence summing correction factors.

9. A spectroscopy analysis system comprising:

a computer processing device configured to execute program instructions comprising:

obtaining output data from at least one photon detection device;

step for calculating a gamma-gamma coincidence summing correction factor and an X-ray coincidence summing correction factor for multiple coincident gamma and X-ray detections; and

applying the X-ray coincidence summing correction factor to the gamma-gamma coincidence summing correction factor to generate corrected full energy peak measurement data; and

transforming the corrected full energy peak measurement data to a visual representation for presentation on a display device for operator review.

10. The system of claim 9 , the program instructions further comprising:

step for calculating an annihilation photon coincidence summing correction factor for coincidences between gamma and annihilation photon detections; and

applying the annihilation photon coincidence summing correction factor to the gamma-gamma coincidence summing correction factor to generate corrected full energy peak measurement data.

11. The system of claim 10 , the program instructions further comprising:

applying the X-ray coincidence summing correction factor and positron-annihilation photon coincidence summing correction factor simultaneously to the gamma-gamma coincidence summing correction factor to generate corrected full energy peak measurement data.

12. The system of claim 10 , the program instructions further comprising:

using a total gamma efficiency in the computation of the gamma-gamma, X-ray gamma, and the annihilation photon-gamma coincidence summing correction factors.

Assignments (9)
SECURITY INTEREST Recorded Oct 22, 2021
From: MIRION TECHNOLOGIES (HOLDINGSUB2), LTD.; MIRION TECHNOLOGIES (USHOLDINGS), INC.; MIRION TECHNOLOGIES (US), INC.; MIRION TECHNOLOGIES (CANBERRA), INC.; MIRION TECHNOLOGIES (CONAX NUCLEAR), INC.; SUN NUCLEAR CORP.; GAMMEX, INC.; MIRION TECHNOLOGIES (IST) CORPORATION; BIODEX MEDICAL SYSTEMS, INC.; MIRION TECHNOLOGIES (CAPINTEC), INC.
To: CITIBANK, N.A., AS COLLATERAL AGENT
Reel/Frame 057890/0509 →
RELEASE OF SECURITY INTEREST Recorded Oct 22, 2021
From: MORGAN STANLEY SENIOR FUNDING, INC.
To: MIRION TECHNOLOGIES (RADOS) GMBH; MIRION TECHNOLOGIES (CANBERRA UK) LTD.; MIRION TECHNOLOGIES (CANBERRA) SAS; MIRION TECHNOLOGIES (CANBERRA), INC.; MIRION TECHNOLOGIES (CANBERRA), INC. (F/K/A CANBERRA INDUSTRIES, INC.); MIRION TECHNOLOGIES (CANBERRA) INC. (F/K/A MIRION TECHNOLOGIES (IMAGING), LLC); MIRION TECHNOLOGIES (IST) CORPORATION; MIRION TECHNOLOGIES, INC.; BIODEX MEDICAL SYSTEMS, INC.; GAMMEX, INC.; SUN NUCLEAR CORP.
Reel/Frame 057890/0970 →
TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENT RIGHTS (SECOND LIEN) Recorded Mar 13, 2019
From: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
To: MIRION TECHNOLOGIES (CANBERRA), INC. (FORMERLY KNOWN AS CANBERRA INDUSTRIES, INC.)
Reel/Frame 049033/0741 →
TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENT RIGHTS (FIRST LIEN) Recorded Mar 13, 2019
From: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
To: MIRION TECHNOLOGIES (CANBERRA), INC. (FORMERLY KNOWN AS CANBERRA INDUSTRIES, INC.)
Reel/Frame 048580/0892 →
SECURITY AGREEMENT Recorded Mar 11, 2019
From: MIRION TECHNOLOGIES (CANBERRA), INC.; MIRION TECHNOLOGIES (IMAGING), LLC; MIRION TECHNOLOGIES (IST) CORPORATION; MIRION TECHNOLOGIES, INC.
To: MORGAN STANLEY SENIOR FUNDING, INC., AS COLLATERAL AGENT
Reel/Frame 048556/0421 →
CHANGE OF NAME Recorded Jan 30, 2017
From: CANBERRA INDUSTRIES INC
To: MIRION TECHNOLOGIES (CANBERRA), INC
Reel/Frame 041550/0236 →
FIRST LIEN GRANT OF SECURITY INTEREST IN PATENT RIGHTS Recorded Aug 9, 2016
From: CANBERRA INDUSTRIES, INC.
To: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH, AS COLLATERAL AGENT
Reel/Frame 039633/0075 →
SECOND LIEN GRANT OF SECURITY INTEREST IN PATENT RIGHTS Recorded Aug 9, 2016
From: CANBERRA INDUSTRIES, INC.
To: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH, AS COLLATERAL AGENT
Reel/Frame 039633/0092 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 3, 2009
From: ZHU, HONGGUO; VENKATARAMAN, RAMKUMAR; MUELLER, WILHELM; LAMONTAGNE, JOSEPH; BRONSON, FRAZIER
To: CANBERRA INDUSTRIES, INC.
Reel/Frame 023462/0025 →