IP Library › Granted Patent US 8,092,859
Granted Patent B2
US 8,092,859 · App. 12/563,900 · Granted Jan 10, 2012

Synthesis of highly luminescent colloidal particles

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Quick Facts
Patent No.
US 8,092,859
App. No.
12/563,900
Granted
Jan 10, 2012
Kind
B2
Abstract

The present invention includes compositions and methods for their used wherein the compositions include clusters of coated fluorescent nanocrystals having a select size formed by controlled aggregation of individual coated nanocrystals.

Claims (18)

1. A method of preparing a nanocrystal aggregate, comprising:

contacting two or more nanocrystals in a solvent, the nanocrystals comprising a coating layer comprising at least one imidazole group;

contacting the nanocrystals to prepare an aggregate of coated nanocrystals;

controlling the aggregate size by modifying the solvent; and

cross-linking the aggregate.

2. The method of claim 1 , wherein the nanocrystals interact through their coating layers.

3. The method of claim 1 , wherein the contacting step further comprises placing the two or more nanocrystals in a solvent mixture.

4. The method of claim 3 , further comprising adjusting the concentration of solvents in the solvent mixture.

5. The method of claim 1 , wherein the size of the aggregate is about 50-80 nm.

6. The method of claim 1 , wherein the aggregate comprises about 2 to about 20 coated nanocrystals.

7. The method of claim 1 , wherein the coating layer comprises a compound selected from histidine, carnosine, glycyl histidine, polyhistidine, polyimidazole, 1,1′-carbonyldiimidazole and 4-imidazoleacrylic acid.

8. The method of claim 1 , wherein the coating layer comprises a compound selected from thiazole, oxazole, pyrrole, thiophene, furan, pyridine, pyrimidine, pyrazine, triazine, triazole, thiophene, phthalocyanine, porphyrin and derivatives thereof.

9. The method of claim 1 , wherein the two or more nanocrystals are semiconductor nanocrystals.

10. A method of preparing a nanocrystal aggregate, comprising:

contacting two or more nanocrystals in a solvent, the nanocrystals comprising a coating layer comprising at least one imidazole group;

contacting the nanocrystals to prepare an aggregate of coated nanocrystals;

controlling the aggregate size by modifying the solvent; and

cross-linking the aggregate, wherein the contacting step further comprises placing the two or more nanocrystals in an aqueous solvent mixture, wherein the aqueous solvent mixture further comprises ethanol.