IP Library Granted Patent US 42,277
Granted Patent E1
US 42,277 · App. 12/571,927 · Granted Apr 5, 2011

Apparatus and method for reducing subcutaneous fat deposits, virtual face lift and body sculpturing by electroporation

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Quick Facts
Patent No.
US 42,277
App. No.
12/571,927
Granted
Apr 5, 2011
Kind
E1
Abstract

An apparatus and method for performing non-invasive treatment of the human face and body by electroporation in lieu of cosmetic surgery is provided. The apparatus comprises a high voltage pulse generator and an applicator having two or more electrodes in close mechanical and electrical contact with the patient's skin for applying the pulses to the patient's skin. The applicator may consist of two pieces with one electrode having a sharp tip and another having a flat surface. High voltage pulses delivered to the electrodes create at the tip of the sharp electrode an electric field high enough to cause death of relatively large subcutaneous fat cells by electroporation. Moving the electrode tip along the skin creates a line of necrotic subcutaneous fat cells, which later are metabolized by the body. Multiple applications of the electrode along predetermined lines on the face or neck create shrinkage of the skin and the subcutaneous fat volume underlying the treated area.

Claims (17)

1. An apparatus for cosmetic treatment comprising:

an applicator including at least one positive and one negative electrode for engaging the skin of a patient and applying a pulsed electric field to the skin and the subcutaneous tissues in a predetermined volume of skin and subcutaneous tissue to be treated;

a power supply for generating high voltage pulses of duration in a range of 10 microseconds to 100 milliseconds for applying a pulsed electric field to the skin and subcutaneous tissues, said pulses having a voltage above the upper electroporation limit of subcutaneous fat cells in the treated volume for the predetermined volume; and

a connector connecting said applicator to said power supply.

2. An apparatus according to claim 1 wherein said applicator includes a plurality of electrodes in an array for applying electric field to the skin and subcutaneous tissues of the patient.

3. An apparatus according to claim 1 wherein said applicator comprises a pair of forceps including a pair of arms and an electrode mounted on each arm, said arms moveable toward and away from one another.

4. An apparatus according to claim 1 wherein said applicator comprises a pair of members, a first one of said members including a needle-like electrode and the second of said members including a flat electrode.

5. An apparatus according to claim 1 wherein the amplitude of the electric field applied to the treated volume falls in a range of 20 Volt/mm to 2000 Volt/mm.

6. An apparatus for providing non-invasive cosmetic surgery to a patient by selectively killing fat cells being found in a predetermined volume of the patient's subcutaneous tissue, said apparatus comprising:

an applicator including at least one positive and one negative electrode for engaging the skin of a patient and applying a pulsed electric field to the skin and the subcutaneous tissues in a predetermined volume of skin and subcutaneous tissue to be treated;

a power supply for generating high voltage pulses of a duration of about 10 microseconds to 100 milliseconds, said high voltage pulses having a voltage above the upper electroporation limit of the preselected fat cells as determined by a minimum size of fat cells to be treated, wherein the pulsed electric field has a voltage amplitude sufficient to irreversibly open pores in the membranes of the preselected fat cells thereby causing death thereto; and

a connector connecting said applicator to said power supply,

wherein said power supply provides said high voltage pulses to said applicator via said connector and wherein application of said pulses to said predetermined volume irreversibly opens pores in fat cells having at least the predetermined minimum size and causes their death.

7. An apparatus according to claim 6 wherein said applicator includes a plurality of electrodes in an array for applying electric field to the skin and subcutaneous tissues of the patient.

8. An apparatus according to claim 6 wherein said applicator comprises a pair of forceps including a pair of arms and an electrode mounted on each arm, said arms moveable toward and away from one another.

9. An apparatus according to claim 6 wherein said applicator comprises a pair of members, a first one of said members including a needle-like electrode and the second of said members including a flat electrode.

10. An apparatus according to claim 6 wherein the amplitude of the electric field applied to the treated volume falls in a range of 20 Volt/mm to 2000 Volt/mm.

Assignments (9)
RELEASE OF SECURITY INTEREST Recorded Jun 8, 2023
From: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
To: ANGIODYNAMICS, INC.
Reel/Frame 063940/0362 →
RELEASE OF SECURITY INTEREST Recorded Aug 31, 2022
From: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
To: ANGIODYNAMICS, INC.
Reel/Frame 061363/0446 →
SECURITY INTEREST Recorded Aug 31, 2022
From: ANGIODYNAMICS, INC.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 061360/0668 →
CONFIRMATORY GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS Recorded Jun 5, 2019
From: ANGIODYNAMICS, INC.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 049371/0657 →
RELEASE OF SECURITY INTEREST Recorded Nov 14, 2016
From: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
To: ANGIODYNAMICS, INC.
Reel/Frame 040688/0540 →
SECURITY INTEREST Recorded Nov 8, 2016
From: ANGIODYNAMICS, INC.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 040613/0049 →
SECURITY AGREEMENT Recorded Sep 30, 2013
From: ANGIODYNAMICS, INC.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 031315/0720 →
RELEASE OF SECURITY INTEREST Recorded Sep 30, 2013
From: JPMORGAN CHASE BANK N.A., AS ADMINISTRATIVE AGENT
To: ANGIODYNAMICS, INC.
Reel/Frame 031315/0361 →
SECURITY AGREEMENT Recorded May 23, 2012
From: ANGIODYNAMICS, INC.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 028260/0329 →