IP Library Granted Patent US 8,391,942
Granted Patent B2
US 8,391,942 · App. 12/574,412 · Granted Mar 5, 2013

Method and apparatus for determining cerebral desaturation in patients undergoing deep hypothermic circulatory arrest

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Quick Facts
Patent No.
US 8,391,942
App. No.
12/574,412
Granted
Mar 5, 2013
Kind
B2
Abstract

A method and apparatus for determining cerebral oxygen saturation in a subject is provided. The method comprises the steps of: a) determining tissue oxygen saturation values using a NIRS type oximeter over a period of time; b) modeling a rate of change in the tissue oxygen saturation values; and c) determining an amount of time until a predetermined tissue oxygen saturation value is reached using the modeling of the tissue oxygen saturation values.

Claims (9)

1. A spectrophotometric examination device, comprising:

at least one sensor having a light signal transmitter operable to transmit at least one light signal, and at least one light signal detector operable to detect the light signal, which sensor is operable to produce at least one sensed signal corresponding to the detected light signal; and

a processor adapted to determine an oxygen saturation level in a subject's tissue at a current point in time using the sensed signal, and which processor is adapted to model a rate of change in oxygen saturation level within the subject's tissue using a non-linear multi-component model, and determine an amount of time between the current point of time and a future point of time when the oxygen saturation level will reach a predetermined value.

2. The device of claim 1 , wherein the processor is adapted to model the rate of change in oxygen saturation level within the subject's tissue on a periodic basis, and update the amount of time between the current point of time and a future point of time in the event of change.

3. A method for determining cerebral oxygen saturation in a subject, comprising the steps of:

determining tissue oxygen saturation values using a NIRS type oximeter over a period of time;

modeling a rate of change in the tissue oxygen saturation values on a non-linear multi-component basis; and

determining an amount of time until a predetermined tissue oxygen saturation value is reached using the modeling of the tissue oxygen saturation values.

4. The method of claim 3 , wherein the step of modeling the rate of change in oxygen saturation level within the subject's tissue is performed on a periodic basis, and includes updating the amount of time until the predetermined tissue oxygen saturation value is reached.

Assignments (11)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 25, 2025
From: EDWARDS LIFESCIENCES CORPORATION; EDWARDS LIFESCIENCES LLC; EDWARDS LIFESCIENCES SÀRL; EDWARDS LIFESCIENCES HOLDING B.V.
To: BD SWITZERLAND SARL
Reel/Frame 072920/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 4, 2019
From: CAS MEDICAL SYSTEMS, INC.
To: EDWARDS LIFESCIENCES CORPORATION
Reel/Frame 050635/0654 →
RELEASE OF SECURITY INTEREST Recorded May 16, 2018
From: SOLAR CAPITAL LTD.
To: CAS MEDICAL SYSTEMS, INC.
Reel/Frame 045823/0342 →
PATENT SECURITY AGREEMENT Recorded Jun 30, 2016
From: CAS MEDICAL SYSTEMS, INC.
To: SOLAR CAPITAL LTD.
Reel/Frame 039221/0004 →
ASSIGNMENT OF INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded May 16, 2016
From: HEALTHCARE FINANCIAL SOLUTIONS, LLC, AS RETIRING AGENT
To: SOLAR CAPITAL LTD., AS SUCCESSOR AGENT
Reel/Frame 038711/0067 →
SECURITY INTEREST Recorded Mar 28, 2016
From: CAS MEDICAL SYSTEMS, INC.
To: HEALTHCARE FINANCIAL SOLUTIONS, LLC (AS SUCCESSOR-IN-INTEREST TO GENERAL ELECTRIC CAPITAL CORPORATION), AS AGENT
Reel/Frame 038115/0439 →
ASSIGNMENT OF INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Nov 15, 2015
From: GENERAL ELECTRIC CAPITAL CORPORATION, AS RETIRING AGENT
To: HEALTHCARE FINANCIAL SOLUTIONS, LLC, AS SUCCESSOR AGENT
Reel/Frame 037112/0159 →
SECURITY INTEREST Recorded Jun 27, 2014
From: CAS MEDICAL SYSTEMS, INC.
To: GENERAL ELECTRIC CAPITAL CORPORATION, AS AGENT
Reel/Frame 033247/0323 →
RELEASE OF SECURITY INTEREST Recorded Jun 30, 2011
From: FIRST NIAGARA BANK, N.A. SUCCESSOR BY MERGER TO NEWALLIANCE BANK
To: CAS MEDICAL SYSTEMS, INC.
Reel/Frame 026525/0955 →
SECURITY AGREEMENT Recorded Mar 25, 2010
From: CAS MEDICAL SYSTEMS, INC.
To: NEWALLIANCE BANK
Reel/Frame 024128/0648 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 2, 2009
From: BENNI, PAUL
To: CAS MEDICAL SYSTEMS, INC.
Reel/Frame 023595/0550 →