Preparation and use of methionylmethionine as feed additive for fish and crustaceans
View Patent ↗An animal feed mixture containing DL-methionyl-DL-methionine and salts thereof for animals kept in aquacultures is provided. Methods for preparing DL-methionyl-DL-methionine of formula (I) and methods to fractionate the diasteriomeric forms obtained are also provided.
1. A feed mixture, comprising from 0.01 to 5% by weight DL/LD methionylmethionine pair of enantiomers or a salt thereof wherein the DL/LD methionylmethionine pair of enantiomers is the only methionyl-methionine pair of enantiomers in the feed mixture;
protein and carbohydrate-obtained from a meal selected from the group consisting of fish meal, soybean meal, corn meal, and mixtures thereof, and,
optionally, a supplement selected from the group consisting of an essential amino acid, a protein, a peptide, a vitamin, a mineral, a carbohydrate, a fat, an oil and a mixture thereof,
wherein the feed is for fish and/or crustaceans farmed in an aquaculture.
2. The feed mixture according to claim 1 , comprising the salt of DL-methionyl-DL-methionine and the salt comprises a cation selected from the group consisting of an alkali metal, an alkaline earth metal, ammonium, Cu 2+ , Zn 2+ , Co 2+ and a mixture thereof.
3. The feed mixture according to claim 1 , further comprising 0.01 to 20% by weight DL-methionine.
4. The feed mixture according to claim 1 which is in the form of a pellet or an extrudate.
5. The feed mixture according to claim 1 , wherein the fish and/or crustaceans are trout, tilapia, or white leg shrimp.
6. The feed mixture according to claim 1 , wherein the fish and/or crustaceans are trout.
7. The feed mixture according to claim 1 , wherein the fish and/or crustaceans are tilapia.
8. The feed mixture according to claim 1 , wherein the fish and/or crustaceans are white leg shrimp.