Compositions and methods for treating or preventing hypoxic or ischemic injury
View Patent ↗A method for treating or preventing injury of a biological material exposed to hypoxic or ischemic conditions comprising contacting the biological material with an effective amount of a compound is disclosed. The compound has the following structure (I): R 1 —(S) n —R 2 (I) or a stereoisomer, pharmaceutically acceptable salt or prodrug thereof, wherein R 1 , R 2 , and n are as defined herein. Compounds, methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
1. A compound having one of the following structures:
2. A pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent in combination with a compound according to claim 1 .
3. A compound having one of the following structures:
4. The compound of claim 3 , wherein the compound has one of the following structures (3-1) or (3-5):
5. A pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent in combination with a compound according to claim 3 .
6. A compound selected from the following structures:
7. A pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent in combination with a compound according to claim 6 .