Medicinal lipolysis of accumulation of fat
Aqueous preparations comprising at least one phospholipid or at least one bile acid and a component assisting degradation of fat such as riboflavin and water are suitable for producing medicaments for removing subcutaneous accumulations of fat and lead to regression of diet-resistant fat pads.
1 . A method for removing subcutaneous accumulations of fat comprising the administration of an efficacious amount of a preparation comprising
(a) at least one bile acid,
(b) a component assisting degradation of fat and
(c) water.
2 . The method of claim 1 , wherein the preparation further comprises an antiinflammatory compound.
3 . A method for the treatment of adipose tissue disorders which are local derangements of fat distribution, the method comprising the removing of subcutaneous accumulations of fat in accordance with the method of claim 1 .
4 . A method for the regression of adipose tissue tumors comprising the removing of subcutaneous accumulation of fat in accordance with the method of claim 1 .
5 . The method of claim 3 , wherein the local derangements of fat distribution are of an unwanted esthetic or pathological nature, and are lipedemas, lipomatosis of the abdominal walls, dermatopanniculosis deformans, xanthelasma, piezogenic nodules or cellulite.
6 . The method of claim 1 , wherein the bile acid employed is selected from the group consisting of deoxycholic acid, cholic acid, lithocholic acid, chenodeoxycholic acid, hyodeoxycholic acid, trihydroxycoprostanic acid, ursodeoxycholic acid, taurocholic acid and glycocholic acid, and the physiologically tolerated salts thereof, or a mixture thereof.
7 . The method of claim 6 , wherein the physiologically tolerated salt of the bile acid employed is its sodium, potassium or ammonium salt.
8 . The method of claim 1 , wherein the component assisting degradation of fat is riboflavin or carnitine or a mixture of these components.
9 . The method of claim 2 , wherein the antiinflammatory compound is tocopherol, diclofenac or triamcinolone or a mixture of these compounds.
10 . The method of claim 1 , wherein the amount of the component assisting degradation of fat in the preparation is from 0.00001 percent by weight to 20 percent by weight.
11 . The method of claim 2 , wherein the amount of the anti-inflammatory compound in the preparation is from 0.00001 percent by weight to 20 percent by weight.
12 . The method of claim 1 , wherein the preparation is administered by subcutaneous, intra-articular, intraperitoneal, intramuscular injection, short infusions or infusion, or by use of the tumenescence technique.
13 . A method for removing subcutaneous accumulations of fat comprising the administration of an efficacious amount of a preparation consisting essentially of
(a) at least one bile acid,
(b) a component assisting degradation of fat and
(c) water.
14 . The method of claim 13 , wherein the bile acid employed is selected from the group consisting of deoxycholic acid, cholic acid, lithocholic acid, chenodeoxycholic acid, hyodeoxycholic acid, trihydroxycoprostanic acid, ursodeoxycholic acid, taurocholic acid and glycocholic acid, and the physiologically tolerated salts thereof, or a mixture thereof.
15 . The method of Claim 14 , wherein the physiologically tolerated salt of the bile acid employed is its sodium, potassium or ammonium salt.
16 . An aqueous system for the treatment of adipose tissue disorders which are local derangements of fat distribution comprising
(a) at least one bile acid,
(b) a component assisting degradation of fat and
(c) water.
17 . The aqueous system of claim 16 , consisting essentially of a bile acid, a component assisting degradation of fat, and water.
18 . The aqueous system of claim 17 , wherein the bile acid is a sodium, a potassium and/or an ammonium salt of deoxycholic acid.