Granted Patent
B2
US 9,133,343 · App. 12/592,639 · Granted Sep 15, 2015
Dyes and compositions, and processes for using same in analysis of protein aggregation and other applications
Inventors:
Wayne Forrest Patton (Dix Hills, NY); Sergiy M. Yarmoluk (Kyiv, UA); Praveen Pande (Holbrook, NY); Vladyslava Kovalska (Kyiv, UA); Lijun Dai (Farmingville, NY); Kateryna Volkova (Kyiv, UA); Jack Coleman (East Northport, NY); Mykhaylo Losytskyy (Kyiv, UA); Anthony Ludlam (Ypsilanti, MI); Anatoliy Balanda (Kyiv, UA)
Assignee:
Enzo Biochem, Inc.
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Abstract
Provided are dyes and compositions which are useful in a number of applications, such as the detection and monitoring protein aggregation, kinetic studies of protein aggregation, neurofibrillary plaques analysis, evaluation of protein formulation stability, protein thermal stability shift assay and analysis of molecular chaperone activity. These dyes and compositions are also useful as probes in nucleic acid and protein detection.
Claims (3)
1. A kit comprising the compounds S25 and TOL-3.
2. The kit of claim 1 , further comprising the compound Yat2150.
3. A kit comprising the compounds S25 and Yat2150.
Assignments (3)
RELEASE OF SECURITY INTEREST
Recorded Jul 24, 2023
From: GEMINO HEALTHCARE FINANCE, LLC D/B/A SLR HEALTHCARE ABL
To: ENZO BIOCHEM, INC.; ENZO CLINICAL LABS, INC.; ENZO LIFE SCIENCES U.S. HOLDING CORP; ENZO LIFE SCIENCES, INC.
Reel/Frame 064369/0031 →
SECURITY INTEREST
Recorded Apr 3, 2023
From: ENZO LIFE SCIENCES, INC.; ENZO CLINICAL LABS, INC.; ENZO BIOCHEM, INC.; ENZO LIFE SCIENCES U.S. HOLDING CORP
To: GEMINO HEALTHCARE FINANCE, LLC D/B/A SLR HEALTHCARE ABL
Reel/Frame 063239/0103 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded May 17, 2012
From: PATTON, WAYNE FORREST; YARMOLUK, SERGIY M.; PANDE, PRAVEEN; KOVALSKA, VLADYSLAVA; DAI, LIJUN; VOLKOVA, KATERYNA; COLEMAN, JACK; LOSYTSKYY, MYKHAYLO; LUDLAM, ANTHONY; BALANDA, ANATOLIY
To: ENZO BIOCHEM, INC.
Reel/Frame 028223/0413 →
Continuity (1)