Radiation Protection Using Single Wall Carbon Nanotube Derivatives
A method of reducing side effects of damage in a human subject exposed to radiation includes administering to the human subject carbon nanotubes in a pharmaceutically acceptable carrier after or prior to exposure to radiation. A composition for reducing radical damage includes a carbon nanotube which is functionalized (1) for substantial water solubility and (2) with a radical trapping agent appended to the carbon nanotube forming a radical scavenger-carbon nanotube conjugate.
1 - 20 . (canceled)
21 . A composition comprising:
a) carbon nanotubes covalently derivatized with a plurality of polymer chains; and
b) molecules sequestered within the plurality of polymer chains.
22 . The composition of claim 21 , wherein polymer chains comprise poly(ethylene glycol).
23 . The composition of claim 21 , wherein the polymer chains comprise poly(ethylene imine).
24 . The composition of claim 21 , wherein the carbon nanotubes are selected from the group consisting of single-wall carbon nanotubes, double-wall carbon nanotubes, multi-wall carbon nanotubes and combinations thereof.
25 . The composition of claim 21 , wherein the sequestered molecules are further associated with the carbon nanotubes by acid-base interactions.
26 . The composition of claim 21 , wherein the sequestered molecules are further associated with the carbon nanotubes by covalent bonding.
27 . The composition of claim 21 , wherein the sequestered molecules are further associated with the carbon nanotubes by pi-pi interactions.
28 . The composition of claim 21 , wherein the sequestered molecules are further associated with the carbon nanotubes by van der Waals interactions.
29 . The composition of claim 21 , wherein the carbon nanotubes are functionalized with a plurality of carboxylic acid groups and each of the plurality of polymer chains is covalently derivatized to the carbon nanotubes through a carboxylic acid group.
30 . The composition of claim 21 , wherein the composition is water soluble.
31 . A water-soluble composition comprising:
a) carbon nanotubes covalently derivatized with a plurality of poly(ethylene glycol) chains; and
b) molecules sequestered within the plurality of poly(ethylene glycol) chains.
32 . The composition of claim 31 , wherein the carbon nanotubes are selected from the group consisting of single-wall carbon nanotubes, double-wall carbon nanotubes, multi-wall carbon nanotubes and combinations thereof.
33 . The composition of claim 31 , wherein the sequestered molecules are further associated with the carbon nanotubes by acid-base interactions.
34 . The composition of claim 31 , wherein the sequestered molecules are further associated with the carbon nanotubes by covalent bonding.
35 . The composition of claim 31 , wherein the carbon nanotubes are functionalized with a plurality of carboxylic acid groups.
36 . A water-soluble composition comprising:
a) carbon nanotubes covalently derivatized with a plurality of poly(ethylene glycol) chains;
wherein the carbon nanotubes comprise a plurality of carboxylic acid groups; and
wherein each of the plurality of poly(ethylene glycol) chains are covalently derivatized to the carbon nanotubes through a carboxylic acid group; and
b) molecules sequestered within the plurality of poly(ethylene glycol) chains.
37 . The composition of claim 36 , wherein the carbon nanotubes are selected from the group consisting of single-wall carbon nanotubes, double-wall carbon nanotubes, multi-wall carbon nanotubes and combinations thereof.
38 . The composition of claim 36 , wherein the sequestered molecules are further associated with the carbon nanotubes by acid-base interactions.
39 . The composition of claim 36 , wherein the sequestered molecules are further associated with the carbon nanotubes by covalent bonding.