IP Library Granted Patent US 8,556,954
Granted Patent B2
US 8,556,954 · App. 12/603,518 · Granted Oct 15, 2013

Methods for treating abnormal growths in the body using a flow reducing implant

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Quick Facts
Patent No.
US 8,556,954
App. No.
12/603,518
Granted
Oct 15, 2013
Kind
B2
Abstract

Methods of using flow reducing implants for treatment of abnormal growths in the body are described. In embodiments of the claimed subject matter, a source blood vessel feeding the abnormal growth is first determined, and a flow reducing implant is then inserted into the source blood vessel to reduce the blood flow through the source blood vessel. The flow reducing implant includes at least one flared section for contacting a blood vessel wall, and at least one narrowed section defining a flow passage. Anchor tabs that lie generally in a plane of the flared section may also be employed.

Claims (19)

1. A method of treating abnormal growth in the body, comprising:

determining a source blood vessel for the abnormal growth;

inserting a flow reducing implant into the source blood vessel, said flow reducing implant including a flared section for contacting a blood vessel wall and a narrowed section defining a flow passage; and

reducing blood flow through the source blood vessel with the flow reducing implant and without completely occluding the source blood vessel, thereby allowing blood flow through the source blood vessel after permanent implantation of the flow reducing implant, and

wherein the reduced blood flow causes ischemia and necrosis of the abnormal growth.

2. A method according to claim 1 , wherein said growth is extant in an organ that is fed from multiple source blood vessels.

3. A method according to claim 1 , wherein said growth is fed by a single source blood vessel.

4. A method according to claim 1 , wherein said growth comprises a leiomyoma.

5. A method according to claim 1 , wherein said growth comprises a malignant tumor.

6. A method according to claim 5 , wherein said tumor is a liver tumor.

7. A method according to claim 5 , wherein said tumor is an encapsulated tumor.

8. A method according to claim 1 , further comprising narrowing the narrowed section after insertion of the flow reducing implant to further reduce blood flow therethrough.

9. A method according to claim 1 , wherein said flow reducing implant is defined by a sheet material with slots, a width of said slots varying over said flow reducing implant to control an expanded geometry of said flow reducing implant.

10. A method of using a flow reducing implant for treatment of an abnormal growth in the body comprising:

determining a source blood vessel for the abnormal growth;

inserting the flow reducing implant into the source blood vessel, said flow reducing implant including a flared section for contacting a blood vessel wall and a narrowed section defining a flow passage; and

reducing blood flow through the source blood vessel with the flow reducing implant and without completely occluding the source blood vessel, thereby allowing blood flow through the source blood vessel after permanent implantation of the flow reducing implant, and

wherein the reduced blood flow causes ischemia and necrosis of the abnormal growth.

11. A method according to claim 10 , wherein said flow reducing implant further includes an anchor tab that lies generally in a plane of said flared section, the method further comprising anchoring the flow reducing implant to the source blood vessel with the anchor tab.

Assignments (7)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 28, 2024
From: NEOVASC MEDICAL LTD.
To: SHOCKWAVE MEDICAL, INC.
Reel/Frame 066942/0164 →
RELEASE OF SECURITY INTEREST Recorded Jun 9, 2020
From: BIO IP VENTURES II LLC, AS COLLATERAL AGENT
To: NEOVASC MEDICAL LTD.
Reel/Frame 052874/0308 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE NAME PREVIOUSLY RECORDED AT REEL: 031850 FRAME: 0858. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Dec 18, 2019
From: BEN-MUVHAR, SHMUEL; SHALEV, ILAN; TSEHORI, JONATHAN; DARVISH, NISSIM
To: NEOVASC MEDICAL LTD.
Reel/Frame 051367/0799 →
DEBENTURE Recorded Apr 27, 2018
From: NEOVASC MEDICAL LTD.
To: BIO IP VENTURES II LLC, AS COLLATERAL AGENT
Reel/Frame 046339/0332 →
RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY COLLATERAL AT REEL/FRAME NO. 41269/0244 Recorded Jan 12, 2018
From: EDWARDS LIFESCIENCES CARDIAQ LLC
To: NEOVASC INC.; NEOVASC TIARA INC.
Reel/Frame 045060/0001 →
SECURITY INTEREST Recorded Jan 5, 2017
From: NEOVASC INC.; NEOVASC TIARA INC.
To: EDWARDS LIFESCIENCES CARDIAQ LLC
Reel/Frame 041269/0244 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 26, 2013
From: BEN MUVHAR, SHMUEL; SHALEV, ILAN; TSEHORI, JONATHAN; DARVISH, NISSIM
To: NEOVASC MEDICAL LTD
Reel/Frame 031850/0858 →