IP Library › Patent Application 12603917
Patent Application
App. No. 12/603,917

Pharmaceutical Pellets Comprising Modified Starch and Therapeutic Applications Therefor

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Quick Facts
Patent No.
US None
App. No.
12/603,917
Abstract

Vaginal use compositions comprising pellets prepared from a debranched starch. Pellets may be conveniently prepared via extrusion/spheronization.

Claims (21)

1 . A vaginal use composition comprising pellets, said pellets comprising a debranched starch and a therapeutic agent.

2 . The composition of claim 1 in the form of a pessary, a tablet or a capsule.

3 . The composition of claim 1 wherein the pellets are prepared by extrusion/spheronization.

4 . The composition of claim 1 wherein the therapeutic agent is a pharmacologically active agent.

5 . The composition of claim 3 wherein the therapeutic agent is mixed in with the debranched starch during the preparation of the pellet.

6 . The composition of claim 1 wherein the therapeutic agent is deposited on the surface of the pellet.

7 . The composition of claim 1 wherein the debranched starch is prepared using a high amylose starch.

8 . The composition of claim 1 wherein the debranched starch is prepared using pullulanase

9 . A method of treating or preventing a condition in a patient comprising administering to a patient a composition comprising pellets, said pellets comprising a debranched starch and a therapeutic agent, wherein sail pellets are administered vaginal.

10 . The method of claim 9 in the form of a pessary, a tablet or a capsule.

11 . The method of claim 9 wherein the pellets are prepared by extrusion/spheronization.

12 . The method of claim 9 wherein the therapeutic agent is a pharmacologically active agent.

13 . The method of claim 11 wherein the therapeutic agent is mixed in with the debranched starch during the preparation of the pellet.

14 . The method of claim 9 wherein the therapeutic agent is deposited on the surface of the pellet.

15 . The method of claim 9 wherein said condition is a vaginal condition

16 . The method of claim 12 wherein said agent is an antifungal agent.

17 . The method of claim 12 wherein said agent is an antibiotic.

18 . The method of claim 12 wherein said agent is an anti-inflammatory agent.

19 . The method of claim 9 wherein the pellets comprise 2 or more therapeutic agents.

20 . The method of claim 19 wherein the pellets contain incompatible drugs.

21 . The method of claim 19 wherein the pellets contain drugs that have different release profiles.