IP Library Granted Patent US 8,440,418
Granted Patent B2
US 8,440,418 · App. 12/620,831 · Granted May 14, 2013

Metabolic syndrome and HPA axis biomarkers for major depressive disorder

Inventors: John Bilello (Durham, NC); Bo Pi (Carlsbad, CA)
Assignee: Ridge Diagnostics, Inc.
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Quick Facts
Patent No.
US 8,440,418
App. No.
12/620,831
Granted
May 14, 2013
Kind
B2
Abstract

Materials and methods for using combinations of metabolic syndrome and HPA axis biomarkers for monitoring major depressive disorder.

Claims (8)

1. A process for diagnosing a human subject as having a depression disorder, comprising:

(a) performing an immunological assay to measure the level of each of EGF, resistin, and cortisol in a blood sample from the subject;

(b) comparing the measured levels of EGF, resistin, and cortisol with control levels of EGF, resistin, and cortisol, respectively, in blood samples; and

(c) diagnosing the subject as having said depression disorder when said measured levels of EGF, resistin, and cortisol are higher than said control levels.

2. The process of claim 1 , wherein said depression disorder is major depressive disorder.

3. The process of claim 1 , wherein said sample is a serum sample.

4. The process of claim 1 , wherein said sample is a plasma sample.

5. The process of claim 1 , wherein the control levels are levels of EGF, resistin, and cortisol in normal human subjects who do not have depression.

Assignments (4)
FORECLOSURE DOCUMENTS Recorded May 24, 2016
From: VINDRAUGA HOLDINGS, LLC
To: VINDRAUGA HOLDINGS, LLC
Reel/Frame 038831/0149 →
SECURITY INTEREST Recorded Jun 15, 2015
From: RIDGE DIAGNOSTICS, INC.
To: VINDRAUGA CORPORATION
Reel/Frame 035854/0162 →
SECURITY AGREEMENT Recorded Nov 8, 2013
From: RIDGE DIAGNOSTICS, INC.
To: VINDRAUGA CORPORATION
Reel/Frame 031601/0321 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 14, 2010
From: BILELLO, JOHN; PI, BO
To: RIDGE DIAGNOSTICS, INC.
Reel/Frame 024234/0658 →
Continuity (2)
Provisional Application 61115710 · Nov 18, 2008
Related Publication 20100136700A1 · Jun 3, 2010