Treatment of chronic lymphocytic leukemia using anti-CD20 antibodies
View Patent ↗Chronic Lymphocytic Leukemia (CLL) may be treated with antibodies directed against the CD20 antigen.
1. A method of treating chronic lymphocytic leukemia (CLL) in a human patient, comprising administering rituximab to the patient in an amount effective to treat the CLL, wherein the rituximab is administered to the patient at a dosage of 500 mg/m 2 .
2. The method of claim 1 further comprising administering a chemotherapeutic regimen to the patient.
3. The method of claim 2 wherein the chemotherapeutic regimen comprises fludarabine.
4. The method of claim 2 wherein the chemotherapeutic regimen comprises cyclosphosphamide.
5. The method of claim 1 wherein the rituximab is administered weekly.
6. The method of claim 1 wherein the rituximab is administered bi-weekly.
7. The method of claim 1 wherein the rituximab is administered monthly.
8. The method of claim 1 which does not include treatment with a radiolabeled anti-CD20 antibody.
9. A method of treating chronic lymphocytic leukemia (CLL) in a human patient, comprising administering rituximab to the patient in an amount effective to treat the CLL, wherein the rituximab is administered to the patient at dosages of 500 mg/m 2 , and further comprising administering a chemotherapeutic regimen to the patient, wherein the chemotherapeutic regimen comprises fludarabine and cyclophosphamide.