IP Library › Granted Patent US 7,956,052
Granted Patent B2
US 7,956,052 · App. 12/630,874 · Granted Jun 7, 2011

Modulators of ATP-binding cassette transporters

Assignee: Vertex Pharmaceuticals Incorporated
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Quick Facts
Patent No.
US 7,956,052
App. No.
12/630,874
Granted
Jun 7, 2011
Kind
B2
Abstract

Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.

Claims (107)

1. A method of treating or lessening the severity of cystic fibrosis in a patient, comprising the step of administering to said patient an effective amount of a compound selected from the following

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Assignments (4)
RELEASE OF SECURITY INTEREST Recorded Oct 14, 2016
From: MACQUARIE US TRADING LLC
To: VERTEX PHARMACEUTICALS INCORPORATED; VERTEX PHARMACEUTICALS (SAN DIEGO) LLC
Reel/Frame 040357/0001 →
ASSIGNEE CHANGE OF ADDRESS Recorded Feb 1, 2016
From: VERTEX PHARMACEUTICALS INCORPORATED
To: VERTEX PHARMACEUTICALS INCORPORATED
Reel/Frame 037676/0031 →
SECURITY INTEREST Recorded Jul 10, 2014
From: VERTEX PHARMACEUTICALS INCORPORATED; VERTEX PHARMACEUTICALS (SAN DIEGO) LLC
To: MACQUARIE US TRADING LLC
Reel/Frame 033292/0311 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 6, 2013
From: HADIDA RUAH, SARA; HAMILTON, MATTHEW; MILLER, MARK; GROOTENHUIS, PETER; BEAR, BRIAN; MCCARTNEY, JASON; ZHOU, JINGLAN; VAN GOOR, FREDRICK
To: VERTEX PHARMACEUTICALS INCORPORATED
Reel/Frame 030558/0602 →
Continuity (6)
Division 11804726 · May 18, 2007
Continuation In Part 11594431 · Nov 8, 2006
Provisional Application 60734506 · Nov 8, 2005
Provisional Application 60754086 · Dec 27, 2005
Provisional Application 60802458 · May 22, 2006
Related Publication 20100087435A1 · Apr 8, 2010