Method for producing fluorinated organic compounds
View Patent ↗Provided is a process for making 2-chloro-1,1,1,2-tetrafluoropropane. The process has the step of hydrofluorinating 2-chloro-3,3,3-trifluoropropene in the presence of a catalyst selected from the group consisting of SbCl 3 , SbCl 5 , SbF 5 , TiCl 4 , SnCl 4 , Cr 2 O 3 , and fluorinated Cr 2 O 3 .
1. A process for making 2-chloro-1,1,1,2-tetrafluoropropane, comprising hydrofluorinating 2-chloro-3,3,3-trifluoropropene in the presence of a catalyst selected from the group consisting of SbCl 3 , SbCl 5 , SbF 5 , TiCl 4 , and SnCl 4 to produce a product composition comprising 2-chloro-1,1,1,2-tetrafluoropropane, wherein the product composition exhibits a 2-chloro-3,3,3-trifluoropropene conversion of about 90% or more and a 2-chloro-1,1,1,2-tetrafluoropropane selectivity of about 80% or more.
2. The process of claim 1 , wherein the catalyst is in bulk form.
3. The process of claim 1 , wherein the catalyst is supported.
4. The process of claim 3 , wherein the support is selected from the group consisting of carbon, alumina, fluorinated alumina, or aluminum fluoride.
5. The process of claim 1 where the catalyst is activated using anhydrous hydrogen fluoride.
6. The process of claim 1 where the catalyst is activated using anhydrous chlorine.
7. The process of claim 1 , wherein the hydrofluorination is vapor-phase fluorination.
8. The process of claim 7 , wherein the catalyst for vapor-phase fluorination reaction is SbCl 5 supported on activated carbon.
9. The process of claim 7 , wherein the vapor-phase fluorination reaction is carried out at a temperature of about 50° C. to about 120° C. and at a pressure of about 30 psia to about 175 psia.
10. The process of claim 7 , wherein the mole ratio of hydrogen fluoride to 2-chloro-3,3,3-trifluoropropene is from about 2:1 to about 15:1.
11. The process of claim 7 , wherein the hydrofluorination of 2-chloro-3,3,3-trifluoropropene is under conditions effective to obtain a conversion of about 90% or more and a 2-chloro-1,1,1,2-tetrafluoropropane selectivity of about 90% or more.
12. The process of claim 1 , wherein the hydrofluorination is liquid-phase fluorination.
13. The process of claim 12 , wherein the catalyst for liquid-phase fluorination reaction is SbCl 5 .
14. The process of claim 12 , wherein the liquid-phase fluorination reaction is carried out at a temperature of about 50° C. to about 120° C. and at a pressure of about 50 psia to about 175 psia.
15. The process of claim 12 , wherein the mole ratio of hydrogen fluoride to 2-chloro-3,3,3-trifluoropropene is from about 2:1 to about 15:1.
16. The process of claim 12 , wherein the hydrofluorination of 2-chloro-3,3,3-trifluoropropene is under conditions effective to obtain a conversion of about 93% or more and a 2-chloro-1,1,1,2-tetrafluoropropane selectivity of about 80% or more.
17. The process of claim 1 , wherein the hydrofluorination of 2-chloro-3,3,3-trifluoropropene is under conditions effective to obtain a conversion of about 93% or more.