Sporicidal hand sanitizing lotion
View Patent ↗A stable, sporicidal hand sanitizer formulation is described. The formulation is a lotion including peracetic acid and one or more short chain alcohols. The lotion demonstrates an extended presence of active PAA and is capable of achieving a total kill of a bacteria in less than about 10 minutes contact time and more particularly, in about 2 minutes contact time.
1. A sporicidal hand sanitizer lotion composition in a stable emulsion form, the composition consisting of:
at least one carboxylic acid selected from the group consisting of acetic acid, propionic acid, citric acid and glutaric acid;
at least one peroxycarboxylic acid;
hydrogen peroxide;
at least one nonionic surfactant;
at least one skin conditioning agent;
at least one fragrance;
water; and
optionally one or more skin treatment compounds, ant-irritant compounds, anionic surfactants, cationic surfactants, thickening agents, solubilizers, emulsifiers, or emollients or a combination thereof, wherein the one or more skin treatment compounds is selected from the group consisting of allantoin, trioctanoin, niacinamide, methyl sulphone and lactose,
wherein after a storage period of 12 months the composition does not separate into different phases and achieves a total kill of a spore forming bacteria in less than about 10 minutes contact time.
2. The composition according to claim 1 , wherein the skin conditioning agent is one or more components selected from glycerol, propylene glycol, sorbitol, aloe vera, lanolin or lanolin-derivatives, petrolatum, cetostearyl alcohol, beeswax, tricaprylin, glyceryl cocoate, isopropyl myristate, or mineral oil.
3. The composition according to claim 1 , wherein the skin conditioning agent is mineral oil or beeswax.
4. The composition according to claim 1 , wherein the carboxylic acid is acetic acid.
5. The composition according to claim 1 , wherein acetic acid is present in an amount from about 1% to about 5% of the total weight of the composition.
6. The composition according to claim 1 , wherein hydrogen peroxide is present in an amount from about 3 wt. % to about 6 wt. % of the total weight of the composition.
7. The composition according to claim 1 , wherein at least one skin conditioning agent is a moisturizing component other than aloe vera.
8. The composition according to claim 1 , wherein the peroxycarboxylic acid is present in the composition in an amount effective to achieve a total kill of a spore-forming bacteria for at least twelve months.
9. The composition according to claim 1 , wherein the composition achieves a total kill of a non-spore forming bacteria in less than about thirty seconds.
10. The composition according to claim 1 , wherein an amount of the fragrance in the composition is less than about 1 wt. % of the total weight of the composition.
11. The composition according to claim 1 , wherein the fragrance is one or more fragrances selected from cuminaldehyde, cinnamic aldehyde, cineole, piperonal or thymol.
12. The composition according to claim 1 , wherein the fragrance is one or more fragrances selected from Rain Forest, Blackberry Sage Tea, Chai Tea, Dewberry, Dogwood, Plumeria, Tranquility, Cucumber Melon, Blackberry, Merlot, Neroli Cedar, Sage and Chamomile or Fresh Cotton.
13. The composition according to claim 1 , wherein the nonionic surfactant is selected from the group consisting of Oleth-35, Glycereth-18, Polysorbate-20, and combinations thereof.
14. The composition according to claim 1 , wherein at least one thickening agent is present.
15. The composition according to claim 1 , wherein the composition achieves a 1-log reduction of a spore forming bacteria in about 4 minutes contact time.
16. The composition according to claim 1 , wherein the composition achieves a 2-log reduction of a spore forming bacteria in about 6 minutes contact time.
17. The composition according to claim 1 , wherein the composition achieves a total kill of a spore forming bacteria in about 5 minutes contact time.
18. The composition according to claim 1 , wherein the composition achieves a total kill of a mycobacteria in less than about 10 minutes contact time.
19. The composition according to claim 1 , wherein the composition achieves a total kill of a vegetative bacteria in less than about 30 seconds contact time.
20. The composition according to claim 1 , wherein the composition achieves a total kill of a fungus in less than about 10 minutes contact time.
21. The composition according to claim 1 , wherein an amount of peroxycarboxylic acid recovered from a surface contacted with the composition is at least 50% after 20 minutes of contact time.
22. The composition according to claim 1 , wherein an amount of peroxycarboxylic acid recovered from a surface contacted with the composition is at greater than about 70% after 3 minutes of contact time.
23. A sporicidal hand sanitizer lotion composition in a stable emulsion form, the composition consisting of:
at least one carboxylic acid selected from the group consisting of acetic acid, propionic acid, citric acid and glutaric acid;
at least one peroxycarboxylic acid;
hydrogen peroxide;
at least one nonionic surfactant;
at least one skin conditioning agent;
at least one fragrance;
water; and
optionally one or more skin treatment compounds, ant-irritant compounds, anionic surfactants, cationic surfactants, thickening agents, solubilizers, emulsifiers, or emollients or a combination thereof, wherein the one or more skin treatment compounds is selected from the group consisting of allantoin, trioctanoin, niacinamide, methyl sulphone and lactose.
24. The composition according to claim 23 , wherein acetic acid is present in an amount from about 1% to about 5% of the total weight of the composition.
25. The composition according to claim 23 , wherein hydrogen peroxide is present in an amount from about 3 wt. % to about 6 wt. % of the total weight of the composition.