Reduced pressure augmentation of microfracture procedures for cartilage repair
View Patent ↗A system for applying a treatment to a defect in one bone of two bones forming a joint that comprises a bladder for delivering a reduced pressure to the defect and for providing a positive pressure as bracing between the two bones of the joint is disclosed. A method for applying such treatment is also disclosed. A bladder for applying such treatment that comprises a reduced-pressure chamber and a bracing chamber is also disclosed.
1. A bladder for applying a treatment to a defect in a first bone or a second bone of two bones forming a joint, the bladder comprising:
a reduced-pressure bladder having an exterior wall forming a reduced-pressure chamber with an interior surface, an opening to the reduced-pressure chamber adapted to substantially surround the defect when positioned against the first bone, and a reduced-pressure port in fluid communication with the reduced pressure chamber for receiving reduced pressure from a source of reduced pressure;
a manifold disposed within the reduced-pressure chamber and having a surface adapted to form a cavity with a portion of the interior surface when reduced pressure is provided to the reduced-pressure chamber and also providing structural support between the interior surface and the exterior wall to prevent the cavity from collapsing, wherein the reduced-pressure bladder seals the opening around the defect that closes the cavity and is thereby exposed to the reduced pressure within the cavity; and
a bracing bladder having an exterior wall forming a bracing chamber for receiving a fluid, a first surface of the exterior wall affixed to the reduced-pressure bladder opposite the opening, a second surface of the exterior wall opposing the first surface adapted to be positioned against the second bone, and a port for providing the fluid to the bracing chamber under a positive pressure, the bracing bladder being inflatable with the fluid to provide a cushion between the reduced-pressure bladder and the second bone when the positive pressure is provided to the bracing chamber.
2. The bladder of claim 1 , wherein the manifold substantially fills the reduced-pressure chamber and includes a surface exposed through the opening for being positioned adjacent the defect.
3. The bladder of claim 2 , wherein the manifold is a foam material in fluid communication with the defect.
4. The bladder of claim 3 , wherein the foam material comprises a plurality of open cells having a size ranging from about 100 microns to about 1,500 microns.
5. The bladder of claim 2 , wherein the first surface of the bracing bladder forms a common wall between the bracing bladder and the reduced-pressure bladder.
6. The bladder of claim 5 , wherein the common wall is substantially inflexible.
7. The bladder of claim 2 , wherein the manifold further comprises a scaffold component sized to fill the defect to facilitate tissue formation in the defect.
8. The bladder of claim 7 , wherein the scaffold component provides additional support between the first bone and the bracing bladder.
9. The bladder of claim 7 , wherein the scaffold component is bioabsorbable.
10. The bladder of claim 9 , wherein the scaffold component adheres to the defect.
11. The bladder of claim 7 , wherein the scaffold component is coated or infused with growth factors or nutrients.
12. The bladder of claim 1 , wherein the reduced pressure bladder and the bracing bladder are comprised of one or more elastomers.
13. The bladder of claim 1 , wherein the manifold partially fills the reduced-pressure chamber.
14. The bladder of claim 13 , wherein the first surface of the bracing bladder forms a common wall between the bracing bladder and the reduced-pressure bladder.
15. The bladder of claim 14 , wherein the common wall is substantially rigid.
16. The bladder of claim 13 , further comprising a foam structure positioned in the cavity to provide additional support between the first bone and the bracing bladder.
17. The bladder of claim 16 , wherein the foam structure is bioabsorbable.
18. The bladder of claim 16 , wherein the foam structure serves as a scaffold for tissue growth.
19. The bladder of claim 18 , wherein the foam structure is coated or infused with growth factors or nutrients.
20. The bladder of claim 16 , wherein the foam structure adheres to the defect.
21. The bladder of claim 1 , further comprising a barrier material covering the opening and closing the cavity, and adapted to directly contact the defect when the reduced-pressure bladder is positioned against the first bone.
22. A bladder for applying a treatment to a defect in a first bone or a second bone of two bones forming a joint, the bladder comprising:
a reduced-pressure bladder having a reduced-pressure port for fluid communication with a source of reduced pressure and an opening sized to substantially surround the defect in the first bone;
a bracing bladder having a positive-pressure port for receiving a fluid under a positive pressure and being affixed to the reduced-pressure bladder;
a manifold disposed within the reduced-pressure bladder and having a surface adapted to form a cavity adjacent the opening for distributing reduced pressure to the defect and providing structural support between the first bone and the bracing bladder to prevent the cavity from collapsing when reduced pressure is provided to the reduced-pressure bladder; and
wherein the bracing bladder inflates with the fluid when positive pressure is applied to the positive-pressure port to provide a cushion between the manifold and the second bone, and wherein the reduced-pressure bladder seals the opening around the defect that closes the cavity and is thereby exposed to the reduced pressure within the cavity when reduced pressure is provided to the reduced-pressure bladder.
23. The bladder of claim 22 , wherein the manifold substantially fills the reduced-pressure bladder and covers the opening in the reduced-pressure bladder whereby the manifold distributes reduced pressure directly to the defect via the opening.
24. The bladder of claim 23 , wherein the manifold is a foam material in fluid communication with the defect.
25. The bladder of claim 24 , wherein the foam material comprises a plurality of open cells have a size ranging from about 100 microns to about 1,500 microns.
26. The bladder of claim 23 , further comprising a common wall between the bracing bladder and the reduced-pressure.
27. The bladder of claim 26 , wherein the common wall is substantially inflexible.
28. The bladder of claim 23 , wherein the manifold further comprises a scaffold component sized to fill the defect to facilitate tissue formation.
29. The bladder of claim 28 , wherein the scaffold component provides additional support between the first bone and the bracing bladder.
30. The bladder of claim 28 , wherein the scaffold component is bioabsorbable.
31. The bladder of claim 30 , wherein the scaffold component adheres to the defect.
32. The bladder of claim 30 , wherein the scaffold component adheres to the manifold.
33. The bladder of claim 28 , wherein the scaffold component is coated or infused with growth factors or nutrients.
34. The bladder of claim 22 , wherein the reduced pressure bladder and the bracing bladder are comprised of one or more elastomers.
35. The bladder of claim 22 , wherein the manifold partially fills the reduced-pressure bladder contacting a portion of the reduced-pressure bladder.
36. The bladder of claim 35 , wherein the manifold is a foam material in fluid communication with the defect.
37. The bladder of claim 36 , wherein the foam material comprises a plurality of open cells have a size ranging from about 100 microns to about 1,500 microns.
38. The bladder of claim 35 , wherein the manifold further comprises a scaffold component sized to fill the defect to facilitate new tissue formation.
39. The bladder of claim 35 , further comprising a common wall between the bracing bladder and the reduced-pressure.
40. The bladder of claim 39 , wherein the common wall is substantially rigid.
41. The bladder of claim 35 , further comprising a foam structure positioned in the cavity to provide additional support between the first bone and the bracing bladder.
42. The bladder of claim 41 , wherein the foam structure is bioabsorbable.
43. The bladder of claim 41 , wherein the foam structure serves as a scaffold for tissue growth.
44. The bladder of claim 41 , wherein the foam material is coated or infused with growth factors or nutrients.
45. The bladder of claim 41 , wherein the foam structure adheres to the manifold.
46. The bladder of claim 22 , further comprising a barrier material covering the opening and closing the cavity, and adapted to directly contact the defect when the reduced-pressure bladder is positioned against the first bone.