IP Library Granted Patent US 7,929,579
Granted Patent B2
US 7,929,579 · App. 12/651,657 · Granted Apr 19, 2011

Picosecond laser apparatus and methods for its operation and use

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Quick Facts
Patent No.
US 7,929,579
App. No.
12/651,657
Granted
Apr 19, 2011
Kind
B2
Abstract

Apparatuses and methods are disclosed for applying laser energy having desired pulse characteristics, including a sufficiently short duration and/or a sufficiently high energy for the photomechanical treatment of skin pigmentations and pigmented lesions, both naturally-occurring (e.g., birthmarks), as well as artificial (e.g., tattoos). The laser energy may be generated with an apparatus having a resonator with the capability of switching between a modelocked pulse operating mode and an amplification operating mode. The operating modes are carried out through the application of a time-dependent bias voltage, having waveforms as described herein, to an electro-optical device positioned along the optical axis of the resonator.

Claims (46)

1. A method for generating pulsed laser energy, the method comprising:

(a) reflecting laser energy generated by a lasing medium between a first mirror at one end of a resonator and a second mirror at the opposite end of said resonator and through a polarizing element and a three terminal Pockels cell within said resonator with the three terminal Pockels cell having a first drive circuit connected to a first end of the Pockels cell and a second drive circuit connected to a second end of the Pockels cell and generating a modelocked pulse within the resonator by the first circuit applying a periodic voltage waveform to the first end of the Pockels cell; and

(b) then amplifying the modelocked pulse by the first circuit applying a first constant voltage to the first end of the Pockels cell and maintaining an effective reflectivity of the second mirror at substantially 100%; and

(c) then extracting the amplified modelocked pulse from the resonator by the second circuit applying a second constant voltage to the second end of the Pockels cell and maintaining an effective reflectivity of the second mirror at substantially 0%.

2. The method of claim 1 , wherein the periodic voltage waveform is equal to the sum of a baseline voltage, V o , and a time-dependent differential voltage, δV(t), that varies periodically with a period substantially equal to the twice the time required for said laser energy to traverse the length of said resonator said baseline voltage V o is from about 30% to about 70% of the quarter wave voltage of the first end of the Pockels cell.

3. The method of claim 2 , wherein said baseline voltage V o is from about 40% to about 60% of the quarter wave voltage of the first end of the Pockels cell.

4. The method of claim 2 , wherein said time-dependent differential voltage, δV(t), has an amplitude from about 5% to about 35% of the quarter wave voltage of the first end of the Pockels cell.

5. The method of claim 2 , wherein said time-dependent differential voltage, δV(t), has an amplitude from about 10% to about 30% of the quarter wave voltage of the first end of the Pockels cell.

6. The method of claim 1 , wherein said first constant voltage is substantially 0 and said second constant voltage is substantially equal to the quarter wave voltage of the second end of the Pockels cell.

7. The method of claim 1 , wherein said pulsed laser energy has at least about 100 mj/pulse.

8. The method of claim 1 , wherein said pulsed laser energy has from about 200 to about 800 mj/pulse.

9. The method of claim 1 , wherein said pulsed laser energy has a pulse duration of at most about 500 ps.

10. The method of claim 1 , wherein said pulsed laser energy has a pulse duration of at most about 150 ps.

11. A method for generating pulsed laser energy, the method comprising:

(a) reflecting laser energy generated by a lasing medium between a first mirror at one end of a resonator and a second mirror at the opposite end of said resonator and through a polarizing element and a first Pockels cell and a second Pockels cell within said resonator with the first Pockels cell connected to a first drive circuit and the second Pockels cell connected to a second drive circuit and generating a modelocked pulse within the resonator by the first circuit applying a periodic voltage waveform to the first Pockels cell; and

(b) then amplifying the modelocked pulse by the first circuit applying a first constant voltage to the first Pockels cell and maintaining an effective reflectivity of the second mirror at substantially 100%; and

(c) then extracting the amplified modelocked pulse from the resonator by the second circuit applying a second constant voltage to the second Pockels cell and maintaining an effective reflectivity of the second mirror at substantially 0%.

12. The method of claim 11 , wherein the periodic voltage waveform is equal to the sum of a baseline voltage, V o , and a time-dependent differential voltage, δV(t), that varies periodically with a period substantially equal to the twice the time required for said laser energy to traverse the length of said resonator said baseline voltage V o is from about 30% to about 70% of the quarter wave voltage of the first Pockels cell.

13. The method of claim 12 , wherein said baseline voltage V o is from about 40% to about 60% of the quarter wave voltage of the first Pockels cell.

14. The method of claim 12 , wherein said time-dependent differential voltage, δV(t), has an amplitude from about 5% to about 35% of the quarter wave voltage of the first Pockels cell.

15. The method of claim 12 , wherein said time-dependent differential voltage, δV(t), has an amplitude from about 10% to about 30% of the quarter wave voltage of the first Pockels cell.

16. The method of claim 11 , wherein said first constant voltage is substantially 0 and said second constant voltage is substantially equal to the quarter wave voltage of the second Pockels cell.

17. The method of claim 11 , wherein said pulsed laser energy has at least about 100 mj/pulse.

18. The method of claim 11 , wherein said pulsed laser energy has from about 200 to about 800 mj/pulse.

19. The method of claim 11 , wherein said pulsed laser energy has a pulse duration of at most about 500 ps.

20. The method of claim 11 , wherein said pulsed laser energy has a pulse duration of at most about 150 ps.

21. A laser apparatus for generating pulsed laser energy comprising:

(a) a resonator having a first mirror at one end of said resonator and a second mirror at the opposite end of said resonator, wherein both said first mirror and said second mirror are substantially totally reflective; and

(b) a lasing medium, a three terminal Pockels cell and a polarizing element along the optical axis of said resonator, wherein a first drive circuit is connected to a first end of the Pockels cell and a second drive circuit is connected to a second end of the Pockels cell,

wherein said apparatus generates a modelocked pulse by the first circuit applying a periodic voltage waveform to the first end of the Pockels cell and then amplifies the modelocked pulse by the first circuit applying a first constant voltage to the first end of the Pockels cell and maintaining an effective reflectivity of the second mirror at substantially 100%, and then extracts the amplified modelocked pulse by the second circuit applying a second constant voltage to the second end of the Pockels cell and maintaining an effective reflectivity of the second mirror at substantially 0%.

22. The apparatus of claim 21 , wherein said pulsed laser energy has at least about 100 mj/pulse.

23. The apparatus of claim 21 , wherein said pulsed laser energy has from about 200 to about 800 mj/pulse.

24. The apparatus of claim 21 , wherein said pulsed laser energy has a pulse duration of at most about 500 ps.

25. The apparatus of claim 21 , wherein said pulsed laser energy has a pulse duration of at most about 150 ps.

26. A laser apparatus for generating pulsed laser energy comprising:

(a) a resonator having a first mirror at one end of said resonator and a second mirror at the opposite end of said resonator, wherein both said first mirror and said second mirror are substantially totally reflective; and

(b) a lasing medium, a first Pockels cell, a second Pockels cell and a polarizing element along the optical axis of said resonator, wherein a first drive circuit is connected to the first Pockels cell and a second drive circuit is connected to the second Pockels cell,

wherein said apparatus generates a modelocked pulse by the first circuit applying a periodic voltage waveform to the first Pockels and then amplifies the modelocked pulse by the first circuit applying a first constant voltage to the first Pockels cell and maintaining an effective reflectivity of the second mirror at substantially 100%, and then extracts the amplified modelocked pulse by the second circuit applying a second constant voltage to the second Pockels cell and maintaining an effective reflectivity of the second mirror at substantially 0%.

27. The apparatus of claim 26 , wherein said pulsed laser energy has at least about 100 mj/pulse.

28. The apparatus of claim 26 , wherein said pulsed laser energy has from about 200 to about 800 mj/pulse.

29. The apparatus of claim 26 , wherein said pulsed laser energy has a pulse duration of at most about 500 ps.

30. The apparatus of claim 26 , wherein said pulsed laser energy has a pulse duration of at most about 150 ps.

31. Electronics for generating and extracting an amplified modelocked pulse within a resonator having a first mirror at one end of said resonator and a second mirror at the opposite end of said resonator, wherein both said first mirror and said second mirror are substantially totally reflective; and with a lasing medium, a three terminal Pockels cell having a first end of the Pockels cell and a second end of the Pockels cell and a polarizing element along the optical axis of said resonator,

the electronics comprising a first drive circuit connected to the first end of the Pockels cell and a second drive circuit connected to the second end of the Pockels cell, with the first circuit applying a periodic voltage waveform to the first end of the Pockels cell and then applying a first constant voltage to the first end of the Pockels cell and the second circuit applying a second constant voltage to the second end of the Pockels cell.

32. Electronics for generating and extracting an amplified modelocked pulse within a resonator having a first mirror at one end of said resonator and a second mirror at the opposite end of said resonator, wherein both said first mirror and said second mirror are substantially totally reflective; and with a lasing medium, a first Pockels cell, a second Pockels cell and a polarizing element along the optical axis of said resonator,

the electronics comprising a first drive circuit connected to the first Pockels cell and a second drive circuit connected to the second Pockels cell, with the first circuit applying a periodic voltage waveform to the first Pockels cell and then applying a first constant voltage to the first Pockels cell and the second circuit applying a second constant voltage to the second Pockels cell.

Assignments (9)
RELEASE OF SECURITY INTEREST Recorded Mar 1, 2024
From: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION
To: CYNOSURE, LLC; PALOMAR MEDICAL TECHNOLOGIES, LLC
Reel/Frame 066723/0227 →
TERMINATION AND RELEASE OF PATENTS Recorded Feb 29, 2024
From: UBS AG, STAMFORD BRANCH, AS COLLATERAL AGENT
To: CYNOSURE, LLC; PALOMAR MEDICAL TECHNOLOGIES, LLC
Reel/Frame 066707/0957 →
ABL NOTICE AND CONFIRMATION OF GRANT OFSECURITY INTEREST IN PATENTS Recorded Jan 12, 2024
From: CYNOSURE, LLC; PALOMAR MEDICAL TECHNOLOGIES, LLC
To: UBS AG, STAMFORD BRANCH, AS COLLATERAL AGENT
Reel/Frame 066222/0937 →
NOTICE AND CONFIRMATION OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Jan 7, 2020
From: CYNOSURE, LLC; PALOMAR MEDICAL TECHNOLOGIES, LLC
To: U.S. BANK NATIONAL ASSOCIATION
Reel/Frame 051496/0579 →
RELEASE OF SECURITY INTEREST IN PATENT RIGHTS Recorded Dec 30, 2019
From: BANK OF AMERICA, N.A.
To: CYNOSURE, LLC
Reel/Frame 051447/0536 →
SECURITY INTEREST Recorded Oct 14, 2019
From: HOLOGIC, INC.; CYNOSURE, LLC; CYTYC CORPORATION; FAXITRON BIOPTICS, LLC; FOCAL THERAPEUTICS, INC.; GEN-PROBE INCORPORATED
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 050719/0701 →
CHANGE OF NAME Recorded Mar 26, 2019
From: CYNOSURE, INC.
To: CYNOSURE, LLC
Reel/Frame 048696/0811 →
SECURITY INTEREST Recorded May 3, 2017
From: CYNOSURE, INC.; PALOMAR MEDICAL TECHNOLOGIES, LLC
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 042261/0911 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 9, 2010
From: HOHM, DANIEL; MIRKOV, MIRKO; WELCHES, RICHARD SHAUN; SIERRA, RAFAEL ARMANDO
To: CYNOSURE, INC.
Reel/Frame 024808/0202 →