IP Library › Granted Patent US 8,697,634
Granted Patent B2
US 8,697,634 · App. 12/654,461 · Granted Apr 15, 2014

Peptides and methods using same for diagnosis and treatment of amyloid-associated disease

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Quick Facts
Patent No.
US 8,697,634
App. No.
12/654,461
Granted
Apr 15, 2014
Kind
B2
Abstract

Peptides having at least 2 amino acids and no more than 15 amino acids are provided. The peptides comprise amino acid sequence X—Y or Y—X, wherein X is an aromatic amino acid and Y is any amino acid other than glycine. Also provided are pharmaceutical compositions and kits including such peptides as well as methods using same for diagnosing and treating amyloid associated diseases.

Claims (6)

1. A synthetic dipeptide as set forth in the general Formula:

wherein:

C* is a chiral carbon having a D configuration;

R 1 and R 2 are each independently selected from the group consisting of alkyl and carboxy;

R 3 is selected from the group consisting of alkoxy and amine; and

R 4 is alkyl substituted by halo.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 28, 2013
From: GAZIT, EHUD
To: TEL AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P.
Reel/Frame 031095/0511 →