Methods for inhibiting sensory responses in the skin such as pain and itch using topical product formulations containing strontium
View Patent ↗Methods for inhibiting sensory responses in the skin such as pain and itch using topical formulations containing aqueous-soluble divalent strontium cation in a suitable topical keratinized skin formulation vehicle are disclosed.
1. A method for reducing irritation comprising the steps of:
preparing a composition comprising:
an aqueous-soluble strontium cation;
a skin penetration enhancer; and
a delivery vehicle; and
topically administering the composition to keratinized skin.
2. The method according to claim 1 , wherein the composition further comprises a counterion.
3. The method according to claim 2 , wherein the counterion further comprises an inorganic anion.
4. The method according to claim 3 , wherein the inorganic anion further comprises a halogen selected from the group consisting of: F, Cl, Br, and I.
5. The method according to claim 3 , wherein the inorganic anion further comprises a nitrate.
6. The method according to claim 4 , wherein the halogen is Cl.
7. The method according to claim 1 , wherein the delivery vehicle is water.
8. The method according to claim 1 , wherein the composition further comprises an organic solvent.
9. The method according to claim 8 , wherein the organic solvent is a glycol.
10. The method according to claim 6 , wherein the delivery vehicle is water.
11. The method according to claim 1 , wherein the irritation results in stinging, burning, itching, redness, swelling or inflammation.