Chemically sensitive field effect transistors and uses thereof in electronic nose devices
View Patent ↗The present invention provides an electronic nose device based on chemically sensitive field effect transistors. In particular, the sensors of the electronic nose device are composed of non-oxidized, functionalized silicon nanowires which can detect volatile organic compounds with very high sensitivity. Methods of use in diagnosing diseases including various types of cancer are disclosed.
1. A system comprising an electronic device comprising an array of chemically sensitive sensors which detect volatile organic compounds in a sample, wherein the chemically sensitive sensors comprise field effect transistors comprising non-oxidized, functionalized silicon nanowires, comprising surface Si atoms and a plurality of functional groups, which form a direct Si—C bond with the silicon nanowires, wherein Si is a surface Si atom and C is a carbon atom of said functional group,
wherein said functional groups are butyl; and
wherein said plurality of functional groups are attached to about 50% of the surface Si atoms.
2. The system according to claim 1 , wherein said chemically sensitive sensors detect volatile organic compounds selected from the group consisting of hexane, heptane, octane, trichloroethylene, ethanol, ethyl acetate.