Antimicrobial compositions
View Patent ↗An environmentally- and user-friendly, aqueous antimicrobial solution comprising effective amounts of hydrogen peroxide, glycolic acid, and at least one antimicrobially-active solvent chosen from benzyl alcohol and phenoxyethanol; concentrated versions of same; kits that can be used to make same; wipes containing same; and the use of same in a method of antimicrobial treatment of a surface contaminated with a microorganism (e.g. bacterial or fungal spore such as C. Difficile ).
1. An antimicrobial solution having a pH from 0.5 to 4 and consisting of:
a. from 3 to 8% w/w hydrogen peroxide;
b. from 0.1 to 6% w/w of glycolic acid;
c. from 2 to 4% w/w of benzyl alcohol
d. optionally, from 0.001 to 5% w/w of at least one non-ionic surfactant;
e. optionally, from 0.01 to 5% w/w of a thickening agent;
f. optionally, from 0.005 to 20% w/w of a hydrogen peroxide stabilizer;
g. optionally, a pH adjuster in an amount sufficient to adjust the pH to within the range of 0.5 to 4;
h. optionally, from an effective amount of at least one ingredient chosen from skin conditioning agents, builders, fragrances, dyes, corrosion inhibitors, additional antimicrobial agents, additional solvents, radical scavengers, soil suspenders, and dye transfer agents; wherein element h. excludes an anionic surfactant;
i. optionally, an effective amount of an amphoteric surfactant, wherein the concentration of all surfactants does not exceed 20% w/w; and
j. water q.s. to 100% w/w.
2. The solution of claim 1 , wherein the glycolic acid is present in a concentration of from 0.1 to 5% w/w.
3. The solution of claim 1 , having a pH of from 2 to 3, and wherein hydrogen peroxide is present in a concentration of from 4 to 7° A) w/w, glycolic acid is present in a concentration of from 1 to 1.5% w/w, and benzyl alcohol is present in a concentration of from 2 to 4% w/w.
4. The solution of claim 1 , having a pH of from 1.5 to 4, and wherein hydrogen peroxide is present in a concentration of from 4 to 7 w/w, glycolic acid is present in a concentration of from 0.5 to 5% w/w, and benzyl alcohol is present in a concentration of from 2 to 4% w/w.
5. The solution of claim 1 , wherein the at least one non-ionic surfactant is present in a concentration of 0.01 to 5% w/w.
6. The solution of claim 1 , wherein the thickening agent is present in a concentration of from 0.01 to 5% w/w.
7. A concentrated solution which can be diluted with water to form an antimicrobial solution having a pH from 0.5 to 4 and consisting of:
a. from 3 to 8% w/w hydrogen peroxide;
b. from 0.1 to 6% w/w of glycolic acid;
c. from 2 to 4% w/w of benzyl alcohol;
d. optionally, from 0.001 to 5% w/w of at least one non-ionic surfactant;
e. optionally, from 0.01 to 5% w/w of a thickening agent;
f. optionally, from 0.005 to 20% w/w of a hydrogen peroxide stabilizer;
g. optionally, a pH adjuster in an amount sufficient to adjust the pH to within the range of 0.5 to 4;
h. optionally, an effective amount of at least one ingredient chosen from skin conditioning agents, builders, fragrances, dyes, corrosion inhibitors, additional antimicrobial agents, additional solvents, radical scavengers, soil suspenders, and dye transfer agents; wherein element h. excludes an anionic surfactant;
i. optionally, an effective amount of an amphoteric surfactant, wherein the concentration of all surfactants does not exceed 20% w/w; and
j. water q.s. to 100% w/w.
8. A disinfecting wipe comprising the solution of claim 1 embedded in a textile medium.
9. A method of antimicrobial treatment of a surface contaminated with a microorganism comprising applying to the surface the solution of claim 1 for a contact time of from 1 to 30 minutes.
10. A method of antimicrobial treatment of a surface contaminated with bacterial or fungal spores comprising applying to the surface the solution of claim 1 for a contact time of from 1 to 30 minutes.
11. A method of antimicrobial treatment of a surface contaminated with C. difficile comprising applying to the surface the solution of claim 1 for a contact time of from 1 to 30 minutes.