Colchicine compositions and methods
View Patent ↗Stable ultrapure colchicine compositions comprising ultrapure colchicine and a pharmaceutically acceptable excipient are described. The compositions can be tablets. Methods for preparing such compositions and methods of use are also disclosed. Methods of treating gout flares with colchicine compositions are also disclosed.
1. A method of treating a gout flare with colchicine in a patient undergoing colchicine prophylactic treatment of gout flares, consisting of
administering to a patient having a gout flare while undergoing prophylactic treatment of gout flares
1.2 mgA oral colchicine at the onset of the acute gout flare, followed by 0.6 mgA oral colchicine about one hour later; and
after waiting 12 hrs, continuing prophylactic treatment consisting of 0.6 mgA or 1.2 mgA oral colchicine daily.