IP Library Granted Patent US 8,388,611
Granted Patent B2
US 8,388,611 · App. 12/687,722 · Granted Mar 5, 2013

Systems and methods for treatment of prostatic tissue

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Quick Facts
Patent No.
US 8,388,611
App. No.
12/687,722
Granted
Mar 5, 2013
Kind
B2
Abstract

A prostate therapy system is provided that may include any of a number of features. One feature of the prostate therapy system is that it can access a prostate lobe transurethrally. Another feature of the prostate therapy system is that it can deliver condensable vapor into the prostate to ablate the prostate tissue. Another feature of the prostate therapy system is that it can aspirate tissue from the prostate. Yet another feature of the prostate therapy system is that it includes a cutter that can rotate during delivery of vapor and aspiration of tissue. Methods associated with use of the prostate therapy system are also covered.

Claims (25)

1. A method for treating a prostate disorder, comprising:

inserting a probe transurethrally into prostatic tissue;

rotating a cutter to volumetrically remove prostatic tissue in at least one lobe of the prostate, substantially without damage to the urethra; and

delivering a vapor from the probe to seal a margin of the removed prostatic tissue.

2. The method of claim 1 wherein the delivering step applies sufficient thermal energy to substantially modify tissue.

3. The method of claim 2 wherein the modification of tissue comprises weakening covalent bonds.

4. The method of claim 2 wherein the modification of tissue comprises denaturing proteins.

5. The method of claim 2 wherein the modification of tissue comprises disrupting collagen structures.

6. The method of claim 1 further comprising imaging the ablation probe.

7. The method of claim 1 wherein an applied energy from the vapor is between approximately 100 W and 1000 W.

8. The method of claim 1 wherein between approximately 10 grams and 50 grams of prostatic tissue are removed during the rotating step.

9. The method of claim 1 wherein an energy release from a phase change in the vapor seals the margin of the removed prostatic tissue.

10. A method for treating a prostate disorder, comprising:

introducing a tissue cutting instrument transurethrally into prostatic tissue;

actuating the tissue cutting instrument and a negative pressure source to cut and extract prostatic tissue; and

delivering a condensable vapor into the prostatic tissue.

11. The method of claim 10 wherein the delivering step applies sufficient thermal energy to substantially modify tissue.

12. The method of claim 11 wherein the modification of tissue comprises weakening covalent bonds.

13. The method of claim 11 wherein the modification of tissue comprises denaturing proteins.

14. The method of claim 11 wherein the modification of tissue comprises disrupting collagen structures.

15. The method of claim 10 wherein the delivering step applies sufficient thermal energy to seal or coagulate margins of the extracted prostatic tissue.

16. The method of claim 10 further comprising imaging the ablation probe.

17. The method of claim 10 wherein an applied energy from the vapor is between approximately 100 W and 1000 W.

18. The method of claim 10 wherein between approximately 10 grams and 50 grams of prostatic tissue are removed during the actuating step.

19. The method of claim 10 wherein an energy release from a phase change in the vapor seals the margin of the removed prostatic tissue during the delivering step.

Assignments (5)
NUNC PRO TUNC ASSIGNMENT Recorded May 21, 2019
From: NXTHERA, INC.
To: BOSTON SCIENTIFIC SCIMED, INC.
Reel/Frame 049240/0378 →
RELEASE OF SECURITY INTEREST Recorded May 16, 2018
From: EAST WEST BANK
To: NXTHERA, INC.
Reel/Frame 045825/0641 →
SECURITY INTEREST Recorded Dec 10, 2015
From: NXTHERA, INC.
To: EAST WEST BANK
Reel/Frame 037265/0505 →
SECURITY INTEREST Recorded Dec 1, 2015
From: NXTHERA, INC.
To: BOSTON SCIENTIFIC CORPORATION
Reel/Frame 037183/0011 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 29, 2010
From: SHADDUCK, JOHN H.; HOEY, MICHAEL
To: NXTHERA, INC.
Reel/Frame 024763/0036 →