Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors
View Patent ↗A process for the preparation of a compound of formula (I) comprising the steps: (a) reacting a compound of formula (II) wherein L and L′ are suitable leaving groups, with a compound of formula (III) UNH 2 (III) to prepare a compound of formula (IV) and subsequently (b) substituting the group R 1 by replacement of the leaving group L′.
1. A compound of the formula
or a pharmaceutically acceptable salt thereof.
2. A pharmaceutical composition, comprising a compound of claim 1 , together with one or more of pharmaceutically acceptable carriers, diluents or excipients.
3. A pharmaceutical composition as claimed in claim 2 in unit dosage form.
4. A compound of the formula
5. A pharmaceutical composition, comprising the compound of claim 4 , together with one or more of pharmaceutically acceptable carriers, diluents or excipients.
6. A pharmaceutical composition as claimed in claim 5 in unit dosage form.
7. A pharmaceutically acceptable salt of the compound of the formula
8. A pharmaceutical composition, comprising the compound of claim 7 , together with one or more of pharmaceutically acceptable carriers, diluents or excipients.
9. A pharmaceutical composition as claimed in claim 7 in unit dosage form.