IP Library Granted Patent US 8,457,440
Granted Patent B1
US 8,457,440 · App. 12/695,029 · Granted Jun 4, 2013

Method and system for background subtraction in medical optical coherence tomography system

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Quick Facts
Patent No.
US 8,457,440
App. No.
12/695,029
Granted
Jun 4, 2013
Kind
B1
Abstract

A method for coherence noise filtering in an optical coherence tomography system comprises generating a background image containing coherence noise, generating a sample image, generating composite pixel values from pixel values in the background image based on the mean pixel values from lines in the background image, and subtracting the composite pixel values from complex pixel values in the sample image.

Claims (44)

1. A method for coherence noise filtering in an optical coherence tomography system, the method comprising:

generating a background image containing coherence noise;

generating a sample image;

generating composite pixel values from pixel values in the background image; and

subtracting the composite pixel values from pixel values in the sample image by generating a corrected sample image by subtracting the magnitude of the composite pixel values from magnitudes of the pixel values in the sample image and leaving a phase of the pixel values in the sample image substantially unchanged.

2. A method as claimed in claim 1 , further comprising performing further processing on the corrected sample image based on the phase of the pixel values.

3. A method as claimed in claim 1 , further comprising performing Doppler velocity extraction of the corrected sample image based on the phase of the pixel values.

4. A method for coherence noise filtering in an optical coherence tomography system, the method comprising:

generating a background image containing coherence noise by taking a background scan with a light block in the optical coherence tomography system and generating the background image by performing an inverse Fourier transform on scan data from the scan of the light block;

generating a sample image;

generating composite pixel values from pixel values in the background image; and

subtracting the composite pixel values from pixel values in the sample image.

5. A method for coherence noise filtering in an optical coherence tomography system, the method comprising:

generating a background image containing coherence noise by cross-correlating different images generated by the optical coherence tomography system;

generating a sample image;

generating composite pixel values from pixel values in the background image; and

subtracting the composite pixel values from pixel values in the sample image.

6. A method for coherence noise filtering in an optical coherence tomography system, the method comprising:

generating a background image containing coherence noise;

generating a sample image by the optical coherence tomography system scanning an optical signal over a sample to generate sample scan fringe data and generating the sample image by performing an inverse Fourier transform on sample scan fringe data;

generating composite pixel values from pixel values in the background image; and

subtracting the composite pixel values from pixel values in the sample image.

7. A method for coherence noise filtering in an optical coherence tomography system, the method comprising:

generating a background image containing coherence noise;

generating a sample image;

generating composite pixel values from pixel values in the background image by taking averages of the pixel values in the background image; and

subtracting the composite pixel values from pixel values in the sample image.

8. A method for coherence noise filtering in an optical coherence tomography system, the method comprising:

generating a background image containing coherence noise;

generating a sample image;

generating composite pixel values from pixel values in the background image by taking averages of the pixel values for lines of the background image; and

subtracting the composite pixel values from pixel values in the sample image.

9. An optical tomography system comprising:

a wavelength swept optical source for generating a tunable optical signal;

an interferometer for transmitting the tunable optical signal from the wavelength swept optical source to a sample arm and reference arm and combining the optical signals from the sample arm and the reference arm to generate an interference signal; and

a processing system that samples the interference signal to generate a sample image and a background image, generates composite pixel values from pixel values in the background image, and subtracts the composite pixel values from pixel values in the sample image.

10. A system as claimed in claim 9 , further comprising a light block in the optical coherence tomography system, the processing system generating the background image by performing an inverse Fourier transform on scan data from the scan of the light block.

11. A system as claimed in claim 9 , wherein the processing system generates the background image by cross-correlating different images generated by the processing system.

12. A system as claimed in claim 9 , further comprising a scanning system for scanning the tunable optical signal over the sample to generate sample scan fringe data; and the processing system generating the sample image by performing an inverse Fourier transform on the sample scan fringe data.

13. A system as claimed in claim 9 , wherein the processing system generates the composite pixel values by taking averages of the pixel values in the background image.

14. A system as claimed in claim 9 , wherein the processing system generates the composite pixel values by taking averages of the pixel values for lines of the background image.

15. A system as claimed in claim 9 , wherein the processing system subtracts a magnitude of the composite pixel values from magnitudes of the pixel values in the sample image, leaving a phase of the pixel values in the sample image substantially unchanged to generate a corrected sample image.

16. A system as claimed in claim 9 , wherein the processing system performs further processing on the corrected sample image based on the phase of the pixel values.

17. A system as claimed in claim 9 , wherein the processing system performs Doppler velocity extraction on the corrected sample image based on the phase of the pixel values.

Assignments (11)
RELEASE OF FIRST LIEN SECURITY INTEREST IN INTELLECTUAL PROPERTY Recorded Aug 12, 2022
From: JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT
To: AXSUN TECHNOLOGIES, INC.
Reel/Frame 061161/0854 →
RELEASE OF SECOND LIEN SECURITY INTEREST IN INTELLECTUAL PROPERTY Recorded Aug 12, 2022
From: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
To: AXSUN TECHNOLOGIES, INC.
Reel/Frame 061161/0942 →
SECURITY INTEREST Recorded Aug 12, 2022
From: EXCELITAS TECHNOLOGIES CORP.
To: GOLUB CAPITAL MARKETS LLC, AS COLLATERAL AGENT
Reel/Frame 061164/0582 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 11, 2020
From: AXSUN TECHNOLOGIES INC.
To: EXCELITAS TECHNOLOGIES CORP.
Reel/Frame 054698/0911 →
FIRST LIEN INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jan 2, 2019
From: AXSUN TECHNOLOGIES, INC.
To: JPMORGAN CHASE BANK, N.A.
Reel/Frame 048000/0692 →
SECOND LIEN INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jan 2, 2019
From: AXSUN TECHNOLOGIES, INC.
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 048000/0711 →
CHANGE OF NAME Recorded Aug 31, 2017
From: AXSUN TECHNOLOGIES, LLC
To: AXSUN TECHNOLOGIES, INC.
Reel/Frame 043733/0195 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 3, 2015
From: VOLCANO CORPORATION
To: AXSUN TECHNOLOGIES, INC.
Reel/Frame 036952/0260 →
CHANGE OF NAME Recorded Nov 3, 2015
From: AXSUN TECHNOLOGIES, INC.
To: AXSUN TECHNOLOGIES LLC
Reel/Frame 037042/0660 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 4, 2014
From: AXSUN TECHNOLOGIES, INC.
To: VOLCANO CORPORATION
Reel/Frame 034101/0321 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 15, 2010
From: JOHNSON, BARTLEY C.
To: AXSUN TECHNOLOGIES, INC.
Reel/Frame 024238/0517 →