Heated nebulizer devices, nebulizer systems, and methods for inhalation therapy
Nebulizer assemblies and systems are disclosed. A nebulizer assembly includes a reservoir and a nebulizer for producing an aerosolized gas. An aerosolized gas outlet passes the aerosolized gas. A breathing gas mixing chamber is coupled to an outlet port of the nebulizer to entrain nebulized medication into a breathing gas. A system and method of heating medication in a reservoir and adding medication to a gas flow is also provided.
1. A nebulizer assembly comprising:
a reservoir for containing a liquid;
a nebulizer for producing an aerosolized gas using the liquid;
an aerosolized gas outlet coupled to the nebulizer to pass the aerosolized gas, the aerosolized gas outlet in fluid communication with a flow of a breathing gas at a junction;
a breathing gas conduit having an inlet end and an outlet end in fluid communication with the junction;
a manifold; and
a heating chamber disposed around an exterior of the reservoir, wherein the heating chamber includes a heating fluid inlet in fluid communication with the heating chamber for providing heating fluid to the heating chamber and a heating fluid outlet in fluid communication with the heating chamber for discharging the heating fluid from the heating chamber, the heating chamber maintaining the heating fluid separate from the liquid contained by the reservoir,
wherein the inlet end of the breathing gas conduit, the heating fluid inlet, and the heating fluid outlet are coupled to the manifold.
2. A method of heating a medication to be nebulized and providing the nebulized medication to a patient for inhalation, the method comprising the steps of:
generating a heated and humidified breathing gas;
transmitting the heated and humidified breathing gas through a first lumen in a delivery tube;
insulating the heated and humidified breathing gas with a fluid flowing through a second lumen in the delivery tube;
discharging the heated and humidified breathing gas from the delivery tube to a chamber;
providing a medication in a nebulizer reservoir;
transmitting the fluid from the second lumen to a heating cavity surrounding the nebulizer reservoir; thereby heating the medication in the nebulizer reservoir with the fluid;
nebulizing the medication in the nebulizer reservoir;
combining the nebulized medication with the heated and humidified breathing gas in the chamber; and
transmitting the combined nebulized medication and heated and humidified breathing gas to a patient for inhalation.
3. The method according to claim 2 , further comprising the step of flowing the fluid from the heating cavity to a third lumen in the delivery tube.
4. A nebulizer system comprising:
a nebulizer for generating an aerosol mist of a medication, wherein the nebulizer is configured to deliver the aerosol mist via a nebulizer outlet port; and
a breathing gas mixing chamber separate from the nebulizer and coupled to the nebulizer outlet port in order to receive the aerosol mist generated by the nebulizer via the nebulizer outlet port, wherein the breathing gas mixing chamber comprises:
a nebulizer coupling port for coupling the breathing gas mixing chamber to the nebulizer outlet port;
a breathing gas inlet adapted to couple to a gas delivery system;
a breathing gas outlet adapted to couple to a breathing device; and
an opening between the breathing gas inlet and the breathing gas outlet, the opening being in fluid communication with the nebulizer outlet port.
5. The nebulizer system according to claim 4 , wherein the breathing gas chamber further comprises a drain port, and further comprising:
a drain collector coupled to the drain port.
6. The nebulizer system according to claim 5 , wherein the drain collector includes a heat moisture exchanger-absorbent media disposed therein.
7. The nebulizer system according to claim 6 , wherein the media changes color responsive to a fluid present in the media.
8. The nebulizer system according to claim 6 , wherein the media comprises an anti-microbial material.
9. The nebulizer system according to claim 4 , wherein the breathing gas mixing chamber further comprises a through-passage extending from the breathing gas inlet to the breathing gas outlet, the through-passage including the opening.
10. The nebulizer system according to claim 4 , wherein the opening comprises a gap.
11. The nebulizer system according to claim 10 , wherein the gap is less than about 5 millimeters.
12. The nebulizer system according to claim 4 , further comprising a nasal cannula coupled to the breathing gas outlet port.
13. The nebulizer system according to claim 12 , wherein the nasal cannula has an overall length of about 4½ inches for neonatal use.
14. A method of adding a medication to a gas flow comprising the steps of:
a) nebulizing the medication with a nebulizer;
b) delivering the nebulized medication from the nebulizer via a nebulizer outlet port;
c) receiving the nebulized medication through a nebulizer coupling port of a breathing gas mixing chamber, the breathing gas mixing chamber separate from the nebulizer, the nebulizer coupling port coupled to the nebulizer outlet port;
d) receiving the gas flow through a breathing gas inlet of the breathing gas mixing chamber; and
e) entraining the nebulized medication into the gas flow.
15. The method according to claim 14 , further comprising the step of passing the entrained, nebulized medication to a nasal cannula.
16. The method according to claim 14 , wherein step (b) comprises:
b1) transmitting the nebulized medication to a breathing gas mixing chamber; and
b2) transmitting the gas flow from an inlet to an outlet within the chamber, the chamber including an opening between the inlet and the outlet, wherein the gas flow draws the nebulized medication into the opening for mixing with the gas flow and passage to the outlet.
17. The method according to claim 16 , further comprising the step of transmitting the gas flow with the nebulized medication to a breathing device for inhalation by a patient.
18. The method according to claim 16 , further comprising the step of collecting nebulized medication not drawn into the gap in a drain collector.
19. The method according to claim 16 , wherein transmitting the gas flow comprises transmitting a heated and humidified gas flow.
20. A nebulizer adaptor for entraining a nebulized medication into a breathing gas, the nebulizer adaptor comprising:
a mixing chamber;
a nebulizer coupling port adapted to be coupled to a nebulizer outlet port and to deliver the nebulized medication from the nebulizer outlet port to the mixing chamber;
a breathing gas inlet adapted to couple to a gas delivery system;
a breathing gas outlet adapted to couple to a breathing device, the breathing gas inlet and breathing gas outlet defining a breathing gas flow path separate from the mixing chamber; and
an opening in the breathing gas flow path between the breathing gas inlet and the breathing gas outlet, the opening being in fluid communication with the mixing chamber.