IP Library Granted Patent US 8,452,545
Granted Patent B2
US 8,452,545 · App. 12/704,594 · Granted May 28, 2013

Method and system for determining the difference between pre-prandial and post-prandial blood glucose values

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Quick Facts
Patent No.
US 8,452,545
App. No.
12/704,594
Granted
May 28, 2013
Kind
B2
Abstract

A method and system is disclosed that enables a less error-prone and preferably automatic assignment of pre-prandial and post-prandial blood glucose values associated with a meal to improve determining the difference between pre-prandial and post-prandial blood glucose measurements as follows. Blood glucose measurements are read and provided with a relative or absolute time mark and labeled as pre-prandial and reading out post-prandial blood glucose measurements provided with a relative or absolute time mark from the memory of a blood glucose measuring instrument. The chronological sequence of the blood glucose measurements labeled as pre-prandial are determined. The post-prandial blood glucose measurements that correspond to each of the pre-prandial blood glucose measurements are determined by applying a time selection criterion. The difference between corresponding pre-prandial and post-prandial blood glucose measurements is determined. The difference values are displayed that have improved diagnostic value.

Claims (39)

1. A method for determining the difference between pre-prandial and post-prandial blood glucose measurements, comprising the steps:

i) reading out blood glucose measurements provided with a relative or absolute time mark and labeled as pre-prandial and reading out other blood glucose measurements provided with a relative or absolute time mark from the memory of a blood glucose measuring instrument;

ii) determining the chronological sequence of the blood glucose measurements labeled as pre-prandial;

iii) determining the post-prandial blood glucose measurement from the other blood glucose measurements that pairs with each of the labeled pre-prandial blood glucose measurements by applying a time selection criterion;

iv) determining difference values between corresponding pairs of pre-prandial and post-prandial blood glucose measurements; and

v) displaying the difference values.

2. The method according to claim 1 , wherein

allocating to time categories corresponding to meals the blood glucose measurements and the difference between corresponding pre-prandial and post-prandial blood glucose measurements.

3. The method according to claim 2 , wherein

the allocation to the time categories is based on the time of the pre-prandial blood glucose measurement.

4. The method according to claim 1 , wherein

determining the chronological sequence of the blood glucose measurements labeled pre-prandial is carried out in ascending order starting with the oldest pre-prandial blood glucose measurement.

5. The method according to claim 1 , wherein

the time selection criteria is a time frame from 60 minutes to 140 minutes starting after the respective labeled pre-prandial blood glucose measurement is used to identify the post-prandial blood glucose measurement.

6. The method according to claim 1 , wherein

if several post-prandial blood glucose measurements are present which fulfill the time selection criterion, the highest blood glucose measurement is used to pair with the corresponding pre-prandial blood glucose measurement.

7. The method according to claim 1 , wherein

steps ii) and iii) proceed in such a manner that

starting with the oldest pre-prandial blood glucose measurement firstly the highest corresponding post-prandial blood glucose measurement is determined;

storing this oldest blood glucose measurement pair for further processing;

determining subsequently the next oldest pre-prandial blood glucose measurement and the highest corresponding post-prandial blood glucose measurement;

storing this next oldest blood glucose measurement pair for further processing; and

repeating these steps until all blood glucose measurements have been taken into consideration up to the most recent pre-prandial blood glucose measurement and, optionally, the highest corresponding post-prandial blood glucose measurement.

8. A system for determining the difference between pre-prandial and post-prandial blood glucose measurements, comprising:

a blood glucose measuring instrument,

a data processing device, and

a computer program having instructions that when executed carry out the following a method for determining the difference between pre-prandial and post-prandial blood glucose measurements,

i) reading out blood glucose measurements provided with a relative or absolute time mark and labeled as pre-prandial and reading out other blood glucose measurements provided with a relative or absolute time mark from the memory of a blood glucose measuring instrument;

ii) determining the chronological sequence of the blood glucose measurements labeled as pre-prandial;

iii) determining the post-prandial blood glucose measurement from the other blood glucose measurements that pairs with each of the labeled pre-prandial blood glucose measurements by applying a time selection criterion;

iv) determining difference values between corresponding pairs of pre-prandial and post-prandial blood glucose measurements; and

v) displaying the difference values.

9. A non-transitory computer program product for determining the difference between pre-prandial and post-prandial blood glucose measurements, comprising:

a non-transitory computer program having instructions that when executed carry out a method for determining the difference between pre-prandial and post-prandial blood glucose measurements,

i) reading out blood glucose measurements provided with a relative or absolute time mark and labeled as pre-prandial and reading out other blood glucose measurements provided with a relative or absolute time mark from the memory of a blood glucose measuring instrument;

ii) determining the chronological sequence of the blood glucose measurements labeled as pre-prandial;

iii) determining the post-prandial blood glucose measurement from the other blood glucose measurements that pairs with each of the labeled pre-prandial blood glucose measurements by applying a time selection criterion;

iv) determining difference values between corresponding pairs of pre-prandial and post-prandial blood glucose measurements; and

v) displaying the difference values.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 23, 2015
From: ROCHE DIAGNOSTICS OPERATIONS, INC.
To: ROCHE DIABETES CARE, INC.
Reel/Frame 036008/0670 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNORS PREVIOUSLY RECORDED ON REEL 024303 FRAME 0663. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jun 8, 2010
From: BLASBERG, PETER; KLOOS, ALFRED; KOEHLER, MATTHIAS
To: ROCHE DIAGNOSTICS GMBH
Reel/Frame 024501/0302 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 28, 2010
From: BLASBERG, PETER; KLOOS, ALFRED
To: ROCHE DIAGNOSTICS GMBH
Reel/Frame 024303/0663 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 28, 2010
From: ROCHE DIAGNOSTICS GMBH
To: ROCHE DIAGNOSTICS OPERATIONS, INC.
Reel/Frame 024303/0695 →