Granted Patent
B2
US 8,003,819 · App. 12/704,830 · Granted Aug 23, 2011
Proteasome inhibitors
Assignee:
Millennium Pharmaceuticals, Inc.
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Abstract
The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
Claims (5)
1. A compound of formula (I):
wherein:
Z 1 and Z 2 together form a moiety derived from a boronic acid complexing agent.
2. A pharmaceutical composition comprising a compound of claim 1 and a pharmaceutically acceptable carrier.
3. A method of treating cancer, comprising administering to a patient in need of such treatment a pharmaceutical composition according to claim 2 .
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Nov 10, 2022
From: MILLENNIUM PHARMACEUTICALS, INC.
To: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Reel/Frame 061726/0250 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Apr 16, 2013
From: OLHAVA, EDWARD J.; DANCA, MIHAELA DIANA
To: MILLENNIUM PHARMACEUTICALS INC.
Reel/Frame 030221/0518 →
Continuity (3)