IP Library Patent Application 12730756
Patent Application
App. No. 12/730,756

FLAVOR EXTRACTING DEVICE FOR ISOLATION OR ANALYSIS OF VOLATILE COMPOUNDS

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Patent No.
US None
App. No.
12/730,756
Abstract

The present invention relates to a solid phase extraction body, methods for its manufacture, uses of such extraction body and analytical methods involving such extraction body.

Claims (71)

1 . A method of producing a solid phase extraction body comprising:

a) forming a mixture comprising

(i) bringing an aromatic polyether into solution in a solvent; and

(ii) suspending a resin in said solvent before, during or after step (a)-(i), wherein the resin is of the formula

−(A) n −(B) m −(C) p −

and salts thereof, wherein the order of (A), (B) and (C) may be random, block, or a combination of random and block; wherein

1

100

<

(

p

+

n

)

m

<

100

1

and

1

500

<

p

n

<

100

1

wherein (A) is selected from the group consisting of

wherein (B) is selected from the group consisting of

and wherein C is A or modified A, wherein modified A is selected from the group consisting of

and X is selected from the group consisting of SO 3 H, CH 2 CO 2 H, CH 2 CH(CO 2 H)— 2 , CO 2 H, PO 3 H 2 , PO 2 H 2 , CH 2 PO 3 H 2 , CH 2 Cl, CH 2 NH 2 , CH 2 N[(CH 2 ) y CH 3 ]— 2 wherein y is any integer from 0 to 18, and CH 2 N + [(CH 2 ) y —CH 3 ] 3 D − wherein y=is any integer from 0 to 18 and D is an anion, SO 2 NHR wherein R is polyethylenimine, or CH 2 NHR wherein R is polyethylenimine, and

b) forming a solid phase extraction body by using the mixture of step a).

2 . The method according to claim 1 , wherein the aromatic polyether is Poly(oxy[1,1′:3′,1″-terphenyl]-2′,5′-diyl)-.

3 . The method according to claim 1 , wherein the solvent is selected from the group consisting of chloroform and dichloromethane.

4 . The method according to claim 1 , wherein the resin is a copolymer of divinylbenzene and N-vinylpyrrolidone.

5 . The method according to claim 15 , wherein the carrier body used in step (b) has a roughness as of glass sand-blasted with corundum of 60 to 120 um particle size at a blasting pressure of 3 bar and an angle of impact of 45°.

6 . The method according to claim 15 , wherein the solid phase extraction layer has an average thickness of 5 to 500 μm.

7 . The method according to claim 1 , further comprising

c) subjecting the resin to a sulfonation reaction so as to form a sulfonated copolymer comprising at least one ion-exchange functional group, at least one hydrophilic component, and at least one hydrophobic component.

8 . A solid phase extraction body obtainable by or obtained by the method according to claim 1 .

9 . The solid phase extraction body according to claim 8 , further comprising a magnetic carrier body.

10 . A solid phase extraction method comprising contacting a medium comprising an analyte with the solid phase extraction body according to claim 8 to allow sorption of the analyte to said solid phase extraction body.

11 . A method for analytically determining the presence of and/or the isolation of an analyte_in a medium, comprising the steps of:

a) contacting the medium comprising the analyte with the solid phase extraction body according to claim 8 to allow sorption of the analyte to the solid phase extraction body;

b) desorbing the analyte from said solid phase extraction body; and

c) detecting or recovering the desorbed analyte.

12 . The method according to claim 11 , wherein the desorption is effected by thermal desorption, and/or wherein the separation and detection is performed quantitatively and/or qualitatively by liquid or gas chromatography

13 . The method according to claim 11 , wherein the medium is selected from the group consisting of flavour and/or fragrance mixtures, foods, food extracts, beverages, culinary preparations, soy, fat-containing foods or food extracts, fruit products, candies, chewing gum, toothpastes, flavors, perfumes, botanical extracts, carbonated and non-carbonated beverages with or without alcohol, cloudy foods, extracts of any kind, biological samples, synthesis products, and intermediate products from production plants.

14 . The method according to claim 1 , wherein

1

500

<

molar

fraction

of

modified

A

n

<

100

1

.

15 . The method according to claim 1 , wherein the solid phase extraction body is formed by coating and drying a carrier body with the mixture of step a) to form a solid phase extraction layer on the carrier body.

Assignments (2)
MERGER Recorded Apr 22, 2011
From: SYMRISE GMBH & CO. KG
To: SYMRISE AG
Reel/Frame 026171/0582 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 9, 2010
From: BRENNECKE, STEFAN; DEGENHARDT, ANDREAS; WEBER, BERTHOLD; KOHLENBERG, BIRGIT; KRAMMER, GERHARD
To: SYMRISE GMBH & CO. KG
Reel/Frame 024511/0314 →